WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573891
Description: Aminomethyltrioxsalen hydrochloride is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.
MedKoo Cat#: 573891
Name: Aminomethyltrioxsalen hydrochloride
Chemical Formula: C15H16ClNO3
Exact Mass: 293.0819
Molecular Weight: 293.75
Elemental Analysis: C, 61.33; H, 5.49; Cl, 12.07; N, 4.77; O, 16.34
Synonym: Aminomethyltrioxsalen hydrochloride, Aminomethyltrioxsalen HCl
IUPAC/Chemical Name: 3-(Aminomethyl)-2,5,9-trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one hydrochloride
InChi Key: HAWQZPVGCLHOBD-UHFFFAOYSA-N
InChi Code: 1S/C15H15NO3.ClH/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15;/h4-5H,6,16H2,1-3H3;1H
SMILES Code: Cl.CC1=CC(=O)Oc2c(C)c3oc(C)c(CN)c3cc12
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 293.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Calvet JP, Pederson T. Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A. 1979 Feb;76(2):755-9. PubMed PMID: 284397; PubMed Central PMCID: PMC383041.