Zolamide sodium

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573869

CAS#: 72296-05-0

Description: Zolamide sodium may be used to prevent and reduce the symptoms of altitude sickness. This drug is also used with other medications to treat open-angle glaucoma due to its efficacy as a diuretic. It decreases the amount of fluid that can build up in the eye. It is also used to decrease a buildup of body fluids (edema) caused by congestive heart failure or certain medications. It has also been used with other medications to treat certain types of seizures (petit mal and unlocalized seizures).


Chemical Structure

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Zolamide sodium
CAS# 72296-05-0

Theoretical Analysis

MedKoo Cat#: 573869
Name: Zolamide sodium
CAS#: 72296-05-0
Chemical Formula: C2H3N4NaO2S2
Exact Mass: 201.9595
Molecular Weight: 202.18
Elemental Analysis: C, 11.88; H, 1.50; N, 27.71; Na, 11.37; O, 15.83; S, 31.71

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 14949-00-9 (free base)  

Synonym: Amino thiadiazole sulfonamide, CL 5343 sodium salt, Tio-urasin sodium, Zolamide sodium

IUPAC/Chemical Name: 1,3,4-Thiadiazole-2-sulfonamide, 5-amino-, monosodium salt

InChi Key: QSGOFQPIEHAARI-UHFFFAOYSA-N

InChi Code: 1S/C2H3N4O2S2.Na/c3-1-5-6-2(9-1)10(4,7)8;/h(H3-,3,4,5,7,8);/q-1;+1

SMILES Code: c1(nnc(s1)S(=O)(=O)[NH-])N.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 202.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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8: Falardeau J, Lobb BM, Golden S, Maxfield SD, Tanne E. The use of acetazolamide during pregnancy in intracranial hypertension patients. J Neuroophthalmol. 2013 Mar;33(1):9-12. doi: 10.1097/WNO.0b013e3182594001. PubMed PMID: 22635167.

9: Kassamali R, Sica DA. Acetazolamide: a forgotten diuretic agent. Cardiol Rev. 2011 Nov-Dec;19(6):276-8. doi: 10.1097/CRD.0b013e31822b4939. Review. PubMed PMID: 21983315.

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