Amifloxacin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573846

CAS#: 86393-37-5 (free base)

Description: Amifloxacin is a fluoroquinolone antibiotic with similar activity to ciprofloxacin.


Chemical Structure

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Amifloxacin
CAS# 86393-37-5 (free base)

Theoretical Analysis

MedKoo Cat#: 573846
Name: Amifloxacin
CAS#: 86393-37-5 (free base)
Chemical Formula: C16H19FN4O3
Exact Mass: 334.14
Molecular Weight: 334.350
Elemental Analysis: C, 57.48; H, 5.73; F, 5.68; N, 16.76; O, 14.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 88036-80-0 (mesylate)   86393-37-5 (free base)    

Synonym: Amifloxacin, Amifloxacine, Win 49375

IUPAC/Chemical Name: 3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-

InChi Key: RUXPNBWPIRDVTH-UHFFFAOYSA-N

InChi Code: 1S/C16H19FN4O3/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20/h7-9,18H,3-6H2,1-2H3,(H,23,24)

SMILES Code: CNn1cc(c(=O)c2c1cc(c(c2)F)N3CCN(CC3)C)C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 334.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Venezia RA, Prymas LA, Shayegani A, Yocum DM. In vitro activities of amifloxacin and two of its metabolites. Antimicrob Agents Chemother. 1989 May;33(5):762-6. PubMed PMID: 2751287; PubMed Central PMCID: PMC172529.

2: Iravani A, Welty GS, Newton BR, Richard GA. Effects of changes in pH, medium, and inoculum size on the in vitro activity of amifloxacin against urinary isolates of Staphylococcus saprophyticus and Escherichia coli. Antimicrob Agents Chemother. 1985 Apr;27(4):449-51. PubMed PMID: 3890724; PubMed Central PMCID: PMC180072.