Amoxicillin embonate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573827

CAS#: 119229-00-4 (embonate)

Description: Amoxicillin embonate is an antibiotic.


Chemical Structure

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Amoxicillin embonate
CAS# 119229-00-4 (embonate)

Theoretical Analysis

MedKoo Cat#: 573827
Name: Amoxicillin embonate
CAS#: 119229-00-4 (embonate)
Chemical Formula: C55H54N6O16S2
Exact Mass: 1,118.30
Molecular Weight: 1,119.180
Elemental Analysis: C, 59.03; H, 4.86; N, 7.51; O, 22.87; S, 5.73

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 26787-78-0 (anhydrous)   34642-77-8 (sodium)   61336-70-7 (hydrate)   119229-00-4 (embonate)    

Synonym: Amoxicillin embonate

IUPAC/Chemical Name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (2:1) (salt)

InChi Key: WXXKGMSZYRAJSK-XSULHWGKSA-N

InChi Code: 1S/C23H16O6.2C16H19N3O5S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;2*1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2*3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t;2*9-,10-,11+,14-/m.11/s1

SMILES Code: CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O.CC4(C)S[C@@H]5[C@H](NC(=O)[C@H](N)c6ccc(O)cc6)C(=O)N5[C@H]4C(=O)O.OC(=O)c7cc8ccccc8c(Cc9c(O)c(cc%10ccccc9%10)C(=O)O)c7O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 1,119.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Attia KA, Nassar MW, El-Zeiny MB, Serag A. Effect of genetic algorithm as a variable selection method on different chemometric models applied for the analysis of binary mixture of amoxicillin and flucloxacillin: A comparative study. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Nov 26;156:54-62. doi: 10.1016/j.saa.2015.11.024. [Epub ahead of print] PubMed PMID: 26641286.

2: Liu Y, Zhu K, Wang J, Huang X, Wang G, Li C, Cao J, Ding S. Simultaneous detection and comparative pharmacokinetics of amoxicillin, clavulanic acid and prednisolone in cows' milk by UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Nov 22;1008:74-80. doi: 10.1016/j.jchromb.2015.11.031. [Epub ahead of print] PubMed PMID: 26638031.

3: Esmaeili-Dooki MR, Shirdel H, Hajiahmadi M. Eradication of Helicobacter pylori in Children by Triple Therapy Regimens of Amoxicillin, Omeprazole, and Clarithromycin or Azithromycin. Iran J Pediatr. 2015 Dec;25(6):e2360. doi: 10.5812/ijp.2360. Epub 2015 Dec 23. PubMed PMID: 26635936; PubMed Central PMCID: PMC4662836.

4: Rodríguez-Félix DE, Castillo-Ortega MM, Nájera-Luna AL, Montaño-Figueroa AG, López-Peña IY, Del Castillo-Castro T, Rodríguez-Félix F, Quiroz-Castilloc JM, Herrera-Franco PJ. Preparation and Characterization of Coaxial Electrospun Fibers Containing Triclosan for Comparative Study of Release Properties with Amoxicillin and Epicatechin. Curr Drug Deliv. 2015 Dec 4. [Epub ahead of print] PubMed PMID: 26634788.

5: Hirte K, Seiwert B, Schüürmann G, Reemtsma T. New hydrolysis products of the beta-lactam antibiotic amoxicillin, their pH-dependent formation and search in municipal wastewater. Water Res. 2015 Nov 14;88:880-888. doi: 10.1016/j.watres.2015.11.028. [Epub ahead of print] PubMed PMID: 26613181.

6: Chadli Z, Ben Fredj N, Youssef M, Chaabane A, Boughattas NA, Zili JE, Aouam K. The rest of the story of the letter to the editors: "Hypersensitivity to amoxicillin after… (DRESS) to carbamazepine…: a possible co-sensitization". Br J Clin Pharmacol. 2015 Nov 23. doi: 10.1111/bcp.12823. [Epub ahead of print] PubMed PMID: 26594014.

7: Park HB, Lee BN, Hwang YC, Hwang IN, Oh WM, Chang HS. Treatment of non-vital immature teeth with amoxicillin-containing triple antibiotic paste resulting in apexification. Restor Dent Endod. 2015 Nov;40(4):322-7. doi: 10.5395/rde.2015.40.4.322. Epub 2015 Aug 28. PubMed PMID: 26587419; PubMed Central PMCID: PMC4650529.

8: Patel AB, Bang A, Singh M, Dhande L, Chelliah LR, Malik A, Khadse S; ISPOT Study Group. A randomized controlled trial of hospital versus home based therapy with oral amoxicillin for severe pneumonia in children aged 3 - 59 months: The IndiaCLEN Severe Pneumonia Oral Therapy (ISPOT) Study. BMC Pediatr. 2015 Nov 17;15:186. doi: 10.1186/s12887-015-0510-9. PubMed PMID: 26577943; PubMed Central PMCID: PMC4650851.

9: Farnier E, Charhon N, Papillon L, Tod M. [Interaction between Amoxicillin Clavulanic Acid and Fluindione: Two Case Reports]. Therapie. 2015 Nov 6. [Epub ahead of print] French. PubMed PMID: 26544165.

10: Ferrer P, Sabaté M, Ballarín E, Fortuny J, Rottenkolber M, Schmiedl S, Laporte JR, Ibáñez L. Sales of macrolides, lincosamides, streptogramins, and amoxicillin/clavulanate in the in- and outpatient setting in 10 European countries, 2007-2010. Springerplus. 2015 Oct 15;4:612. doi: 10.1186/s40064-015-1398-4. eCollection 2015. PubMed PMID: 26543747; PubMed Central PMCID: PMC4628133.