R 151885

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 585079

CAS#: 76674-14-1

Description: R 151885 delays ovulation in rats.


Chemical Structure

img
R 151885
CAS# 76674-14-1

Theoretical Analysis

MedKoo Cat#: 585079
Name: R 151885
CAS#: 76674-14-1
Chemical Formula: C16H13F2N3O
Exact Mass: 301.1027
Molecular Weight: 301.2968
Elemental Analysis: C, 63.78; H, 4.35; F, 12.61; N, 13.95; O, 5.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: R 151885; R151885; R-151885

IUPAC/Chemical Name: 1H-1,2,4-Triazole-1-ethanol, alpha,alpha-bis(4-fluorophenyl)-

InChi Key: OGZYWIZILQBEJI-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H13F2N3O/c17-14-5-1-12(2-6-14)16(22,9-21-11-19-10-20-21)13-3-7-15(18)8-4-13/h1-8,10-11,22H,9H2

SMILES Code: OC(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)CN3N=CN=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 301.2968 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Milne CM, Hasmall RL, Russell A, Watson SC, Vaughan Z, Middleton MC. Reduced estradiol production by a substituted triazole results in delayed ovulation in rats. Toxicol Appl Pharmacol. 1987 Sep 30;90(3):427-35. PubMed PMID: 3310336.

2: Wickings EJ, Middleton MC, Hillier SG. Non-steroidal inhibition of granulosa cell aromatase activity in vitro. J Steroid Biochem. 1987 Jun;26(6):641-6. PubMed PMID: 3112466.

3: Middleton MC, Milne CM, Moreland S, Hasmall RL. Ovulation in rats is delayed by a substituted triazole. Toxicol Appl Pharmacol. 1986 Apr;83(2):230-9. PubMed PMID: 3083533.