WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 558695
Description: PSB-15160 is a potent orthosteric and allosteric agonist of GPR84.
MedKoo Cat#: 558695
Chemical Formula: C17H12F2N2
Exact Mass: 282.0969
Molecular Weight: 282.29
Elemental Analysis: C, 72.33; H, 4.28; F, 13.46; N, 9.92
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: PSB 15160; PSB15160; PSB-15160
IUPAC/Chemical Name: Di(5-fluoro-1H-indole-3-yl)methane; 3,3'-Methylenebis(5-fluoro-1H-indole)
InChi Key: BEBUKYWOUXBVEE-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H12F2N2/c18-12-1-3-16-14(6-12)10(8-20-16)5-11-9-21-17-4-2-13(19)7-15(11)17/h1-4,6-9,20-21H,5H2
SMILES Code: FC1=CC(C(CC2=CNC3=C2C=C(F)C=C3)=CN4)=C4C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 282.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pillaiyar T, Köse M, Sylvester K, Weighardt H, Thimm D, Borges G, Förster I, von Kügelgen I, Müller CE. Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84. J Med Chem. 2017 May 11;60(9):3636-3655. doi: 10.1021/acs.jmedchem.6b01593. Epub 2017 May 1. PubMed PMID: 28406627.