PSB-16671

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558693

CAS#: NONE

Description: PSB-16671 is a potent orthosteric and allosteric agonist of GPR84.

Chemical Structure

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PSB-16671
CAS# NONE
Instruction

Theoretical Analysis

MedKoo Cat#: 558693
Name: PSB-16671
CAS#: NONE
Chemical Formula: C17H10F4N2
Exact Mass: 318.078
Molecular Weight: 318.27
Elemental Analysis: C, 64.15; H, 3.17; F, 23.88; N, 8.80

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: PSB-16671; PSB 16671; PSB16671

IUPAC/Chemical Name: Di(5,7-difluoro-1H-indole-3-yl)methane

InChi Key: VOZFGFKTXNHCLF-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H10F4N2/c18-10-2-12-8(6-22-16(12)14(20)4-10)1-9-7-23-17-13(9)3-11(19)5-15(17)21/h2-7,22-23H,1H2

SMILES Code: FC1=CC(F)=CC2=C1NC=C2CC3=CNC4=C3C=C(F)C=C4F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 318.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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1: Mancini SJ, Mahmud ZA, Jenkins L, Bolognini D, Newman R, Barnes M, Edye ME, McMahon SB, Tobin AB, Milligan G. On-target and off-target effects of novel orthosteric and allosteric activators of GPR84. Sci Rep. 2019 Feb 12;9(1):1861. doi: 10.1038/s41598-019-38539-1. PubMed PMID: 30755705; PubMed Central PMCID: PMC6372602.

2: Pillaiyar T, Köse M, Sylvester K, Weighardt H, Thimm D, Borges G, Förster I, von Kügelgen I, Müller CE. Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84. J Med Chem. 2017 May 11;60(9):3636-3655. doi: 10.1021/acs.jmedchem.6b01593. Epub 2017 May 1. PubMed PMID: 28406627.

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PSB-16671