p32-IN-M36

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MedKoo CAT#: 558670

CAS#: 802555-85-7

Description: p32-IN-M36 is an inhibitor of p32 mitochondrial protein, which binds directly to p32 and blocks p32 association with LyP-1.


Chemical Structure

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p32-IN-M36
CAS# 802555-85-7

Theoretical Analysis

MedKoo Cat#: 558670
Name: p32-IN-M36
CAS#: 802555-85-7
Chemical Formula: C23H28N8O2
Exact Mass: 448.2335
Molecular Weight: 448.53
Elemental Analysis: C, 61.59; H, 6.29; N, 24.98; O, 7.13

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: p32 IN-M36; p32-IN M36; p32-IN-M36; p32 inhibitor M36

IUPAC/Chemical Name: 1,1'-(Propane-1,3-diyl)bis(3-(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea)

InChi Key: HHFOXYBNULCICF-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H28N8O2/c32-22(30-18-6-1-4-16(14-18)20-24-10-11-25-20)28-8-3-9-29-23(33)31-19-7-2-5-17(15-19)21-26-12-13-27-21/h1-2,4-7,14-15H,3,8-13H2,(H,24,25)(H,26,27)(H2,28,30,32)(H2,29,31,33)

SMILES Code: O=C(NC1=CC=CC(C2=NCCN2)=C1)NCCCNC(NC3=CC=CC(C4=NCCN4)=C3)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 448.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Yenugonda V, Nomura N, Kouznetsova V, Tsigelny I, Fogal V, Nurmemmedov E, Kesari S, Babic I. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210. doi: 10.1186/s12967-017-1312-7. PubMed PMID: 29047383; PubMed Central PMCID: PMC5648515.