CBB3001

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565781

CAS#: 1639358-50-1

Description: CBB3001 is a selective lysine-specific histone demethylase LSD1 inhibitor.

Chemical Structure

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CBB3001
CAS# 1639358-50-1
Instruction

Theoretical Analysis

MedKoo Cat#: 565781
Name: CBB3001
CAS#: 1639358-50-1
Chemical Formula: C19H27NO5
Exact Mass: 349.19
Molecular Weight: 349.427
Elemental Analysis: C, 65.31; H, 7.79; N, 4.01; O, 22.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: CBB3001; CBB 3001; CBB-3001

IUPAC/Chemical Name: tert-Butyl trans-2-(4-(tert-butoxycarbonyloxy)phenyl)cyclopropylcarbamate

InChi Key: VVFYDJJSFHIMKO-LSDHHAIUSA-N

InChi Code: InChI=1S/C19H27NO5/c1-18(2,3)24-16(21)20-15-11-14(15)12-7-9-13(10-8-12)23-17(22)25-19(4,5)6/h7-10,14-15H,11H2,1-6H3,(H,20,21)/t14-,15+/m0/s1

SMILES Code: O=C(OC(C)(C)C)N[C@H]1[C@H](C2=CC=C(OC(OC(C)(C)C)=O)C=C2)C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 349.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hoang N, Zhang X, Zhang C, Vo V, Leng F, Saxena L, Yin F, Lu F, Zheng G, Bhowmik P, Zhang H. New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells. Bioorg Med Chem. 2018 May 1;26(8):1523-1537. doi: 10.1016/j.bmc.2018.01.031. Epub 2018 Feb 7. PubMed PMID: 29439916; PubMed Central PMCID: PMC6071666.

2: Jostes S, Nettersheim D, Schorle H. Epigenetic drugs and their molecular targets in testicular germ cell tumours. Nat Rev Urol. 2019 Apr;16(4):245-259. doi: 10.1038/s41585-019-0154-x. Review. PubMed PMID: 30765888.