AM-3102
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MedKoo CAT#: 573764

CAS#: 213182-22-0

Description: AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.


Chemical Structure

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AM-3102
CAS# 213182-22-0

Theoretical Analysis

MedKoo Cat#: 573764
Name: AM-3102
CAS#: 213182-22-0
Chemical Formula: C21H41NO2
Exact Mass: 339.3137
Molecular Weight: 339.56
Elemental Analysis: C, 74.28; H, 12.17; N, 4.12; O, 9.42

Price and Availability

Size Price Availability Quantity
5.0mg USD 215.0 2 Weeks
10.0mg USD 360.0 2 Weeks
50.0mg USD 735.0 2 Weeks
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Synonym: AM-3102, AM3102, AM 3102, KDS-5104, Methyl oleoylethanolamide

IUPAC/Chemical Name: 9-Octadecenamide, N-((1R)-2-hydroxy-1-methylethyl)-, (9Z)-

InChi Key: IPVYNYWIRWMRHH-JPMGXVIASA-N

InChi Code: 1S/C21H41NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21(24)22-20(2)19-23/h10-11,20,23H,3-9,12-19H2,1-2H3,(H,22,24)/b11-10-/t20-/m1/s1

SMILES Code: CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](C)CO

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 339.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Orio L, Alen F, Pavón FJ, Serrano A, García-Bueno B. Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse. Front Mol Neurosci. 2019 Jan 9;11:490. doi: 10.3389/fnmol.2018.00490. eCollection 2018. Review. PubMed PMID: 30687006; PubMed Central PMCID: PMC6333756.

2: Bowen KJ, Kris-Etherton PM, Shearer GC, West SG, Reddivari L, Jones PJH. Oleic acid-derived oleoylethanolamide: A nutritional science perspective. Prog Lipid Res. 2017 Jul;67:1-15. doi: 10.1016/j.plipres.2017.04.001. Epub 2017 Apr 5. Review. PubMed PMID: 28389247.

3: Brown JD, Karimian Azari E, Ayala JE. Oleoylethanolamide: A fat ally in the fight against obesity. Physiol Behav. 2017 Jul 1;176:50-58. doi: 10.1016/j.physbeh.2017.02.034. Epub 2017 Feb 27. Review. PubMed PMID: 28254531.

4: Zhou H, Yang WS, Li Y, Ren T, Peng L, Guo H, Liu JF, Zhou Y, Zhao Y, Yang LC, Jin X. Oleoylethanolamide attenuates apoptosis by inhibiting the TLR4/NF-κB and ERK1/2 signaling pathways in mice with acute ischemic stroke. Naunyn Schmiedebergs Arch Pharmacol. 2017 Jan;390(1):77-84. doi: 10.1007/s00210-016-1309-4. Epub 2016 Oct 13. PubMed PMID: 27738712.

AM-3102

5.0mg / USD 215.0