WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565689
Description: IA-alkyne is a novel thiol-reactive and clickable proble for protein-protein interaction studies
MedKoo Cat#: 565689
Chemical Formula: C8H12INO
Exact Mass: 264.9964
Molecular Weight: 265.0945
Elemental Analysis: C, 36.25; H, 4.56; I, 47.87; N, 5.28; O, 6.04
IA-alkyne is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Synonym: IA-alkyne; IA alkyne; IAalkyne
IUPAC/Chemical Name: N-(5-Hexyn-1-yl)-2-iodoacetamide
InChi Key: YCRUVTMZPHEOAM-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H12INO/c1-2-3-4-5-6-10-8(11)7-9/h1H,3-7H2,(H,10,11)
SMILES Code: O=C(NCCCCC#C)CI
The following data is based on the product molecular weight 265.0945 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Abo M, Li C, Weerapana E. Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling. Mol Pharm. 2018 Mar 5;15(3):743-749. doi: 10.1021/acs.molpharmaceut.7b00832. Epub 2017 Dec 6. PubMed PMID: 29172527; PubMed Central PMCID: PMC5841085.