WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565670
Description: WYC-209 is a novel inhibitor of tumor-repopulating cells (trcs), inducing trc apoptosis primarily via the caspase 3 pathway
MedKoo Cat#: 565670
Chemical Formula: C22H22O3S
Exact Mass: 366.129
Molecular Weight: 366.475
Elemental Analysis: C, 72.10; H, 6.05; O, 13.10; S, 8.75
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: WYC-209; WYC 209; WYC209
IUPAC/Chemical Name: Ethyl 4-((4,4-dimethyl-1-oxidothiochroman-6-yl)ethynyl)benzoate
InChi Key: BTLUWTPBBDYOKU-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H22O3S/c1-4-25-21(23)18-10-7-16(8-11-18)5-6-17-9-12-20-19(15-17)22(2,3)13-14-26(20)24/h7-12,15H,4,13-14H2,1-3H3
SMILES Code: O=C(OCC)C1=CC=C(C#CC2=CC(C(C)(C)CCS3=O)=C3C=C2)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 366.475 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Chen J, Cao X, An Q, Zhang Y, Li K, Yao W, Shi F, Pan Y, Jia Q, Zhou W, Yang F, Wei F, Wang N, Yu B. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406. doi: 10.1038/s41467-018-03877-7. PubMed PMID: 29643385; PubMed Central PMCID: PMC5895803.