AM-92016 HCl
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MedKoo CAT#: 555585

CAS#: 133229-11-5 (HCl)

Description: AM-92016 is an oxypropanolamine analogue of sotalol, has been shown to possess Class III anti-arrhythmic properties in-vitro at concentrations showing 1000 times more potency than sotalol. AM 92016 exhibited proarrhythmic rather than antiarrhythmic activity when administered in-vivo to either guinea-pigs or pigs.


Price and Availability

Size Price Shipping out time Quantity
25mg USD 250 2 Weeks
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 1950 2 Weeks
1g USD 3250 2 Weeks
2g USD 5850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-11-23. Prices are subject to change without notice.

AM-92016 HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555585
Name: AM-92016 HCl
CAS#: 133229-11-5 (HCl)
Chemical Formula: C19H25Cl3N2O4S
Exact Mass:
Molecular Weight: 483.829
Elemental Analysis: C, 47.17; H, 5.21; Cl, 21.98; N, 5.79; O, 13.23; S, 6.63


Related CAS #: 133229-23-9 (free base)   133229-11-5 (HCl)    

Synonym: AM-92016 HCl; AM 92016 HCl; AM92016 HCl; AM-92016 hydrochloride

IUPAC/Chemical Name: N-(4-(3-((3,4-dichlorophenethyl)(methyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide hydrochloride

InChi Key: TXOARFPCQOBODS-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H24Cl2N2O4S.ClH/c1-23(10-9-14-3-8-18(20)19(21)11-14)12-16(24)13-27-17-6-4-15(5-7-17)22-28(2,25)26;/h3-8,11,16,22,24H,9-10,12-13H2,1-2H3;1H

SMILES Code: OC(CN(C)CCC1=CC=C(Cl)C(Cl)=C1)COC2=CC=C(NS(=O)(C)=O)C=C2.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Katsuki H, Shinohara A, Fujimoto S, Kume T, Akaike A. Tetraethylammonium
exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures. Eur J
Pharmacol. 2005 Jan 31;508(1-3):85-91. Epub 2005 Jan 6. PubMed PMID: 15680257.

2: Hagerty MJ, Wainwright CL, Kane KA. The in-vivo cardiovascular effects of a
putative class III anti-arrhythmic drug, AM 92016. J Pharm Pharmacol. 1996
Apr;48(4):417-21. PubMed PMID: 8794994.