OD36 hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565615

CAS#: 1638644-62-8

Description: OD36 hydrochloride is a novel potent and selective receptor-interacting protein kinase 2 (ripk2) inhibitor

Chemical Structure

OD36 hydrochloride
CAS# 1638644-62-8

Theoretical Analysis

MedKoo Cat#: 565615
Name: OD36 hydrochloride
CAS#: 1638644-62-8
Chemical Formula: C16H16Cl2N4O2
Exact Mass: 366.065
Molecular Weight: 367.23
Elemental Analysis: C, 52.33; H, 4.39; Cl, 19.31; N, 15.26; O, 8.71

Price and Availability

Size Price Availability Quantity
10.0mg USD 385.0 2 Weeks
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Synonym: OD36 hydrochloride; OD36 HCl

IUPAC/Chemical Name: 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride


InChi Code: InChI=1S/C16H15ClN4O2.ClH/c17-12-7-11-8-13(9-12)23-6-5-22-4-2-18-15-1-3-21-16(20-15)14(11)10-19-21;/h1,3,7-10H,2,4-6H2,(H,18,20);1H


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 367.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Tigno-Aranjuez et al (2014) In vivo inhibition of RIPK2 kinase alleviates inflammatory disease. J.Biol.Chem. 289 29651 PMID: 25213858

2. Sánchez-Duffhues et al (2019) Development of macrocycle kinase inhibitors for ALK2 using Fibrodysplasia ossificans progressiva-derived endothelial cells. JBMRPlus 3 e10230 PMID: 31768489