CAND1-Cullin1 destabilizer C60

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MedKoo CAT#: 565569

CAS#: N/A

Description: CAND1-Cullin1 destabilizer C60 is a novel destabilizer of cand1-cullin1 interaction, inducing a p53-stress response pathway


Chemical Structure

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CAND1-Cullin1 destabilizer C60
CAS# N/A

Theoretical Analysis

MedKoo Cat#: 565569
Name: CAND1-Cullin1 destabilizer C60
CAS#: N/A
Chemical Formula: C27H24ClN3O4
Exact Mass: 489.1455
Molecular Weight: 489.956
Elemental Analysis: C, 66.19; H, 4.94; Cl, 7.24; N, 8.58; O, 13.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: CAND1-Cullin1 destabilizer C60; CAND1 Cullin1 destabilizer C60; CAND1-Cullin1-destabilizer-C60

IUPAC/Chemical Name: Methyl 2-[[6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carbonyl]amino]benzoate

InChi Key: QKKLITDYULGDTP-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H24ClN3O4/c1-34-18-10-7-16(8-11-18)25-24-19(21-15-17(28)9-12-23(21)29-24)13-14-31(25)27(33)30-22-6-4-3-5-20(22)26(32)35-2/h3-12,15,25,29H,13-14H2,1-2H3,(H,30,33)

SMILES Code: O=C(OC)C1=CC=CC=C1NC(N(C2C3=CC=C(OC)C=C3)CCC4=C2NC5=C4C=C(Cl)C=C5)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 489.956 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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4: Alder RW, Harvey JN, Schleyer PR, Moran D. T(h)-symmetrical N8(C=C)6 and P8(C=C)6; an extraordinary contrast in heterofullerene stability. Org Lett. 2001 Oct 18;3(21):3233-6. PubMed PMID: 11594802.