UCPH-102F

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MedKoo CAT#: 565524

CAS#: N/A

Description: UCPH-102F is a fluorescent excitatory amino acid transporter subtype 1 (eaat1) selective inhibitor


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-29. Prices are subject to change without notice.

UCPH-102F is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565524
Name: UCPH-102F
CAS#: N/A
Chemical Formula: C24H25N3O4
Exact Mass: 419.1845
Molecular Weight: 419.481
Elemental Analysis: C, 68.72; H, 6.01; N, 10.02; O, 15.26


Synonym: UCPH-102F; UCPH 102F; UCPH102F

IUPAC/Chemical Name: 2'-Amino-7-(diethylamino)-4'-methyl-2,5'-dioxo-5',6',7',8'-tetrahydro-2H,4'H-[4,7'-bichromene]-3'-carbonitrile

InChi Key: QJLRINQORPQZLU-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H25N3O4/c1-4-27(5-2)15-6-7-16-17(11-22(29)30-20(16)10-15)14-8-19(28)23-13(3)18(12-25)24(26)31-21(23)9-14/h6-7,10-11,13-14H,4-5,8-9,26H2,1-3H3

SMILES Code: N#CC1=C(N)OC2=C(C(CC(C(C3=C(O4)C=C(N(CC)CC)C=C3)=CC4=O)C2)=O)C1C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Erichsen MN, Hansen J, Ruiz JA, Demmer CS, Abrahamsen B, Bastlund JF, Bundgaard C, Jensen AA, Bunch L. Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs. Neurochem Res. 2014 Oct;39(10):1964-79. doi: 10.1007/s11064-014-1264-8. Epub 2014 Feb 28. PubMed PMID: 24682739.

2: Huynh TH, Abrahamsen B, Madsen KK, Gonzalez-Franquesa A, Jensen AA, Bunch L. Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102. Bioorg Med Chem. 2012 Dec 1;20(23):6831-9. doi: 10.1016/j.bmc.2012.09.049. Epub 2012 Oct 2. PubMed PMID: 23072958.