WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573752
Description: Alprafenone is a Class I anti-arrythmic agent.
MedKoo Cat#: 573752
Chemical Formula: C25H35NO4
Exact Mass: 413.2566
Molecular Weight: 413.56
Elemental Analysis: C, 72.61; H, 8.53; N, 3.39; O, 15.47
This product is not in stock, which may be available by custom synthesis.
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IUPAC/Chemical Name: (+-)-3-(3-(2-Hydroxy-3-(tert-pentylamino)propoxy)-4-methoxyphenyl)-4'-methylpropiophenone
InChi Key: WUUQBRHWNUFEEB-UHFFFAOYSA-N
InChi Code: 1S/C25H35NO4/c1-6-25(3,4)26-16-21(27)17-30-24-15-19(10-14-23(24)29-5)9-13-22(28)20-11-7-18(2)8-12-20/h7-8,10-12,14-15,21,26-27H,6,9,13,16-17H2,1-5H3
SMILES Code: c1c(c(OC)ccc1CCC(=O)c1ccc(C)cc1)OC[C@@H](CNC(C)(CC)C)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 413.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Anyukhovsky EP, Rosen MR. Electrophysiologic effects of alprafenone on canine cardiac tissue. J Cardiovasc Pharmacol. 1994 Sep;24(3):411-9. PubMed PMID: 7528297.
2: Rose H, Ionescu I, Pöpping S, Fischer Y, Kammermeier H. Negative inotropic effects of the new class I antiarrhythmic agents berlafenone and alprafenone on electrically stimulated isolated cardiomyocytes. Arzneimittelforschung. 1992 Mar;42(3):289-91. PubMed PMID: 1497686.