PUN51207
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555566

CAS#: 1784751-20-7

Description: PUN51207, also known as CK1-IN-1, is a casein kinase 1 (CK1) inhibitor. PUN51207 was reported in patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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PUN51207
CAS# 1784751-20-7
Instruction

Theoretical Analysis

MedKoo Cat#: 555566
Name: PUN51207
CAS#: 1784751-20-7
Chemical Formula: C24H15F2N3
Exact Mass: 383.12
Molecular Weight: 383.400
Elemental Analysis: C, 75.19; H, 3.94; F, 9.91; N, 10.96

Price and Availability

Size Price Availability Quantity
500mg USD 2250
1g USD 3250
2g USD 5850
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Synonym: PUN51207; PUN-51207; PUN 51207; CK1-IN-1; CK1-IN1; CK1-IN 1;

IUPAC/Chemical Name: Pyridine, 4-[2-(1-fluoro-2-naphthalenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-

InChi Key: PUQAFIILJICJRR-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H15F2N3/c25-18-8-5-16(6-9-18)22-23(17-11-13-27-14-12-17)29-24(28-22)20-10-7-15-3-1-2-4-19(15)21(20)26/h1-14H,(H,28,29)

SMILES Code: FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C5C=CC=CC5=C4F)=N2)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 0.00

Preparing Stock Solutions

The following data is based on the product molecular weight 383.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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