WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555561

CAS#: 959860-85-6

Description: BUN60856, also known as cFMS Receptor Inhibitor II, is a cFMS inhibitor. This product has not formal name. For the convenience of scientific communication, we named it by combining its Inchi key (3 letters from the first letter of each section) with the last 5 digits of its CAS number or its molecule weight if its CAS number is not available (see MedKoo Chemical Nomenclature, https://www.medkoo.com/page/naming).

Chemical Structure

CAS# 959860-85-6

Theoretical Analysis

MedKoo Cat#: 555561
Name: BUN60856
CAS#: 959860-85-6
Chemical Formula: C23H20N4O
Exact Mass: 368.1637
Molecular Weight: 368.44
Elemental Analysis: C, 74.98; H, 5.47; N, 15.21; O, 4.34

Price and Availability

Size Price Availability Quantity
200.0mg USD 1450.0 2 Weeks
500.0mg USD 2250.0 2 Weeks
1.0g USD 3850.0 2 Weeks
2.0g USD 6450.0 2 Weeks
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Synonym: cFMS Receptor Inhibitor II; BUN60856; BUN-60856; BUN 60856;

IUPAC/Chemical Name: 4-[(3,4-Dimethylphenyl)amino]-7-(4-pyridinyl)-3-quinolinecarboxamide


InChi Code: InChI=1S/C23H20N4O/c1-14-3-5-18(11-15(14)2)27-22-19-6-4-17(16-7-9-25-10-8-16)12-21(19)26-13-20(22)23(24)28/h3-13H,1-2H3,(H2,24,28)(H,26,27)

SMILES Code: O=C(C1=C(NC2=CC=C(C)C(C)=C2)C3=CC=C(C4=CC=NC=C4)C=C3N=C1)N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 368.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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200.0mg / USD 1450.0

Additional Information

1. Compositions and methods for obtaining enriched mesenchymal stem cell cultures. By Short, Brenton John; Duronio, Christopher. From U.S. Pat. Appl. Publ. (2016), US 20160032248 A1 20160204.

2. Preparation of enriched mesenchymal stem cell cultures using CSF1R kinase inhibitors. By Short, Brenton John; Duronio, Christopher. From PCT Int. Appl. (2014), WO 2014138888 A1 20140918.

3. 3D-​QSAR analysis of anilinoquinoline inhibitors of colony stimulating factor-​1 kinase (cFMS)​: implementation of field-​based molecular alignment
By Kumari, Archana; Kaur, Maninder; Bahia, Malkeet Singh; Silakari, Om. From Medicinal Chemistry Research (2013), 22(11), 5167-5183.

4. Synthesis of novel anilinoquinolines as c-​fms inhibitors. By Smalley, Terrence L.; Chamberlain, Stanley D.; Mills, Wendy Y.; Musso, David L.; Randhawa, Sab A.; Ray, John A.; Samano, Vicente; Frick, Lloyd. From Bioorganic & Medicinal Chemistry Letters (2007), 17(22), 6257-6260.