Nitrefazole
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MedKoo CAT#: 573703

CAS#: 21721-92-6

Description: Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase. This enzyme crucial to the metabolism of alcohol and is suitable for aldehyde dehydrogenase (ALDH) related research.


Price and Availability

Size Price Shipping out time Quantity
250mg USD 325 2 Weeks
2g USD 1575 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-11-23. Prices are subject to change without notice.

Nitrefazole, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 573703
Name: Nitrefazole
CAS#: 21721-92-6
Chemical Formula: C10H8N4O4
Exact Mass: 248.0546
Molecular Weight: 248.2
Elemental Analysis: C, 48.39; H, 3.25; N, 22.57; O, 25.78


Synonym: Altimol, BT-985, EMD 15 700, EMD 15700, EMD-15,700; Nitrefazol, Nitrefazole, Nitrefazolum

IUPAC/Chemical Name: 1H-Imidazole, 2-methyl-4-nitro-1-(4-nitrophenyl)- (9CI)

InChi Key: NMTBSNPBIGRZBL-UHFFFAOYSA-N

InChi Code: 1S/C10H8N4O4/c1-7-11-10(14(17)18)6-12(7)8-2-4-9(5-3-8)13(15)16/h2-6H,1H3

SMILES Code: Cc1nc(cn1c2ccc(cc2)[N+](=O)[O-])[N+](=O)[O-]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Suokas A, Kupari M, Pettersson J, Lindros K. The nitrefazole-ethanol interaction in man: cardiovascular responses and the accumulation of acetaldehyde and catecholamines. Alcohol Clin Exp Res. 1985 May-Jun;9(3):221-7. PubMed PMID: 3893193.

2: Stockwell T, Sutherland G, Edwards G. The impact of a new alcohol sensitizing agent (nitrefazole) on craving in severely dependent alcoholics. Br J Addict. 1984 Dec;79(4):403-9. PubMed PMID: 6598964.