Caprylic/capric triglyceride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581920

CAS#: 65381-09-1

Description: Caprylic/capric triglyceride is a biochmeical.


Chemical Structure

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Caprylic/capric triglyceride
CAS# 65381-09-1

Theoretical Analysis

MedKoo Cat#: 581920
Name: Caprylic/capric triglyceride
CAS#: 65381-09-1
Chemical Formula: C21H40O5
Exact Mass: 372.29
Molecular Weight: 372.55
Elemental Analysis: C, 67.70; H, 10.82; O, 21.47

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Caprylic/capric triglyceride; Caprylic acid, capric acid triglyceride; Glycerol octanoate decanoate

IUPAC/Chemical Name: Decanoic acid, ester with 1,2,3-propanetriol octanoate

InChi Key: YOYOQXRPUDEPAK-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H40O5/c1-3-5-7-9-10-12-14-16-21(24)26-19(17-22)18-25-20(23)15-13-11-8-6-4-2/h19,22H,3-18H2,1-2H3

SMILES Code: OCC(OC(CCCCCCCCC)=O)COC(CCCCCCC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 372.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Maurya VK, Aggarwal M. A phase inversion based nanoemulsion fabrication process to encapsulate vitamin D3 for food applications. J Steroid Biochem Mol Biol. 2019 Jun;190:88-98. doi: 10.1016/j.jsbmb.2019.03.021. Epub 2019 Mar 25. PubMed PMID: 30923018.

2: Esposito E, Pecorelli A, Sguizzato M, Drechsler M, Mariani P, Carducci F, Cervellati F, Nastruzzi C, Cortesi R, Valacchi G. Production and Characterization of Nanoparticle Based Hyaluronate Gel Containing Retinyl Palmitate for Wound Healing. Curr Drug Deliv. 2018;15(8):1172-1182. doi: 10.2174/1567201815666180518123926. PubMed PMID: 29779480.

3: Esposito E, Sguizzato M, Bories C, Nastruzzi C, Cortesi R. Production and Characterization of a Clotrimazole Liposphere Gel for Candidiasis Treatment. Polymers (Basel). 2018 Feb 8;10(2). pii: E160. doi: 10.3390/polym10020160. PubMed PMID: 30966196; PubMed Central PMCID: PMC6414984.

4: Benvegnú DM, Roversi K, Barcelos RCS, Trevizol F, Pase CS, Segat HJ, Dias VT, Savian AL, Piccoli BL, Piccolo J, Dutra-Filho CS, Emanuelli T, de Bona da Silva C, Beck RCR, Burger ME. Effects of Fish and Grape Seed Oils as Core of Haloperidol-Loaded Nanocapsules on Oral Dyskinesia in Rats. Neurochem Res. 2018 Feb;43(2):477-487. doi: 10.1007/s11064-017-2444-0. Epub 2017 Dec 5. PubMed PMID: 29209877.

5: Abd El-Hamid BN, Swarnakar NK, Soliman GM, Attia MA, Pauletti GM. High payload nanostructured lipid carriers fabricated with alendronate/polyethyleneimine ion complexes. Int J Pharm. 2018 Jan 15;535(1-2):148-156. doi: 10.1016/j.ijpharm.2017.10.064. Epub 2017 Nov 8. PubMed PMID: 29104057.

6: Zhao H, Liu C, Quan P, Wan X, Shen M, Fang L. Mechanism study on ion-pair complexes controlling skin permeability: Effect of ion-pair dissociation in the viable epidermis on transdermal permeation of bisoprolol. Int J Pharm. 2017 Oct 30;532(1):29-36. doi: 10.1016/j.ijpharm.2017.08.080. Epub 2017 Aug 19. PubMed PMID: 28830782.

7: Esposito E, Sguizzato M, Drechsler M, Mariani P, Carducci F, Nastruzzi C, Cortesi R. Progesterone lipid nanoparticles: Scaling up and in vivo human study. Eur J Pharm Biopharm. 2017 Oct;119:437-446. doi: 10.1016/j.ejpb.2017.07.015. Epub 2017 Jul 29. PubMed PMID: 28760448.

8: Savić V, Todosijević M, Ilić T, Lukić M, Mitsou E, Papadimitriou V, Avramiotis S, Marković B, Cekić N, Savić S. Tacrolimus loaded biocompatible lecithin-based microemulsions with improved skin penetration: Structure characterization and in vitro/in vivo performances. Int J Pharm. 2017 Aug 30;529(1-2):491-505. doi: 10.1016/j.ijpharm.2017.07.036. Epub 2017 Jul 12. PubMed PMID: 28711641.

9: Sato MR, Oshiro Junior JA, Machado RT, de Souza PC, Campos DL, Pavan FR, da Silva PB, Chorilli M. Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis. Drug Des Devel Ther. 2017 Mar 20;11:909-921. doi: 10.2147/DDDT.S127048. eCollection 2017. PubMed PMID: 28356717; PubMed Central PMCID: PMC5367736.

10: Hernandes MRG, Moraes LCA, Ribeiro EB, Fagundes DLG, Honorio-França AC, França EL. In vitro immunomodulatory effects of microemulsions with levamisole delivery systems on blood phagocytes interacting with Giardia lamblia. Parasitol Int. 2017 Jun;66(3):299-304. doi: 10.1016/j.parint.2017.02.005. Epub 2017 Feb 28. PubMed PMID: 28257952.

11: Leite-Silva VR, Sanchez WY, Studier H, Liu DC, Mohammed YH, Holmes AM, Ryan EM, Haridass IN, Chandrasekaran NC, Becker W, Grice JE, Benson HA, Roberts MS. Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment. Eur J Pharm Biopharm. 2016 Jul;104:140-7. doi: 10.1016/j.ejpb.2016.04.022. Epub 2016 Apr 27. PubMed PMID: 27131753.

12: Cavalcanti AL, Reis MY, Silva GC, Ramalho ÍM, Guimarães GP, Silva JA, Saraiva KL, Damasceno BP. Microemulsion for topical application of pentoxifylline: In vitro release and in vivo evaluation. Int J Pharm. 2016 Jun 15;506(1-2):351-60. doi: 10.1016/j.ijpharm.2016.04.065. Epub 2016 Apr 27. PubMed PMID: 27130362.

13: Lu XX, Chen WR, Li N, Liu ZC, Long XY. [Preparation and Dissolution Evaluation of Breviscapine Self-microemulsion]. Zhong Yao Cai. 2015 Apr;38(4):821-6. Chinese. PubMed PMID: 26672352.

14: Chen Y, Tuo J, Huang H, Liu D, You X, Mai J, Song J, Xie Y, Wu C, Hu H. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. Int J Pharm. 2015 Jun 20;487(1-2):17-24. doi: 10.1016/j.ijpharm.2015.03.075. Epub 2015 Apr 1. PubMed PMID: 25841571.

15: Nikolakakis I, Panagopoulou A, Salis A, Malamataris S. Relationships between the properties of self-emulsifying pellets and of the emulsions used as massing liquids for their preparation. AAPS PharmSciTech. 2015 Feb;16(1):129-39. doi: 10.1208/s12249-014-0214-8. Epub 2014 Sep 12. PubMed PMID: 25212898; PubMed Central PMCID: PMC4309816.

16: Milović M, Simović S, Lošić D, Dashevskiy A, Ibrić S. Solid self-emulsifying phospholipid suspension (SSEPS) with diatom as a drug carrier. Eur J Pharm Sci. 2014 Oct 15;63:226-32. doi: 10.1016/j.ejps.2014.07.010. Epub 2014 Aug 11. PubMed PMID: 25125211.

17: Dezzutti CS, Russo J, Wang L, Abebe KZ, Li J, Friend DR, McGowan IM, Rohan LC. Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation. PLoS One. 2014 Jul 15;9(7):e102585. doi: 10.1371/journal.pone.0102585. eCollection 2014. PubMed PMID: 25025306; PubMed Central PMCID: PMC4099179.

18: You X, Xing Q, Tuo J, Song W, Zeng Y, Hu H. Optimizing surfactant content to improve oral bioavailability of ibuprofen in microemulsions: just enough or more than enough? Int J Pharm. 2014 Aug 25;471(1-2):276-84. doi: 10.1016/j.ijpharm.2014.05.031. Epub 2014 May 22. PubMed PMID: 24858390.

19: Jaworska M, Sikora E, Zielina M, Ogonowski J. Studies on the formation of O/W nano-emulsions, by low-energy emulsification method, suitable for cosmeceutical applications. Acta Biochim Pol. 2013;60(4):779-82. PubMed PMID: 24432331.

20: Vyumvuhore R, Tfayli A, Manfait M, Baillet-Guffroy A. Vibrational spectroscopy coupled to classical least square analysis, a new approach for determination of skin moisturizing agents' mechanisms. Skin Res Technol. 2014 Aug;20(3):282-92. doi: 10.1111/srt.12117. Epub 2013 Nov 21. PubMed PMID: 24256135.