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MedKoo CAT#: 408016

CAS#: 1621535-90-7

Description: UCM-1336 is a potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor ( IC50 = 2 μM). UCM-1336 improves survival in Ras-driven acute myeloid leukemia. UCM-1336 significantly impairs the membrane association of the four Ras isoforms, leading to a decrease of Ras activity and to inhibition of Ras downstream signaling pathways. In addition, it induces cell death in a variety of Ras-mutated tumor cell lines and increases survival in an in vivo model of acute myeloid leukemia.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

UCM-1336 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 408016
Name: UCM-1336
CAS#: 1621535-90-7
Chemical Formula: C26H37N3O2
Exact Mass: 423.2886
Molecular Weight: 423.6
Elemental Analysis: C, 73.72; H, 8.80; N, 9.92; O, 7.55

Synonym: UCM-1336; UCM 1336; UCM1336;

IUPAC/Chemical Name: 3,3'-(octylazanediyl)bis(N-phenylpropanamide)


InChi Code: InChI=1S/C26H37N3O2/c1-2-3-4-5-6-13-20-29(21-18-25(30)27-23-14-9-7-10-15-23)22-19-26(31)28-24-16-11-8-12-17-24/h7-12,14-17H,2-6,13,18-22H2,1H3,(H,27,30)(H,28,31)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: