M119

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565340

CAS#: NONE

Description: M119 is a potent Gβγ modulator.


Chemical Structure

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M119
CAS# NONE

Theoretical Analysis

MedKoo Cat#: 565340
Name: M119
CAS#: NONE
Chemical Formula: C20H18O7
Exact Mass: 370.1053
Molecular Weight: 370.36
Elemental Analysis: C, 64.86; H, 4.90; O, 30.24

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: M-119; M 119; M119; NSC119910; NSC 119910; NSC-119910; Gbetagamma Modulator I

IUPAC/Chemical Name: 2-(3,4,5-Trihydroxy-6-oxoxanthen-9-yl)cyclohexane-1-carboxylic acid

InChi Key: CAVIJGGXNIURPI-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H18O7/c21-13-7-5-11-15(9-3-1-2-4-10(9)20(25)26)12-6-8-14(22)17(24)19(12)27-18(11)16(13)23/h5-10,21,23-24H,1-4H2,(H,25,26)

SMILES Code: O=C(C1C(C(C2=C(OC3=C4O)C(O)=C(O)C=C2)=C3C=CC4=O)CCCC1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 370.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Han C, Li Y, Wang Y, Cui D, Luo T, Zhang Y, Ma Y, Wei W. Development of Inflammatory Immune Response-Related Drugs Based on G Protein-Coupled Receptor Kinase 2. Cell Physiol Biochem. 2018;51(2):729-745. doi: 10.1159/000495329. Epub 2018 Nov 21. Review. PubMed PMID: 30463058.