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MedKoo CAT#: 565338

CAS#: 92-78-4

Description: nAS-E is an inhibitor of the KIX-KID interaction and CREB-mediated gene transcription.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-09-20. Prices are subject to change without notice.

nAS-E, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data, and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 565338
Name: nAS-E
CAS#: 92-78-4
Chemical Formula: C17H12ClNO2
Exact Mass: 297.0557
Molecular Weight: 297.74
Elemental Analysis: C, 68.58; H, 4.06; Cl, 11.91; N, 4.70; O, 10.75

Synonym: Naphthol AS-E; nAS-E; nAS E

IUPAC/Chemical Name: N-(4-Chlorophenyl)-3-hydroxy-2-naphthamide


InChi Code: InChI=1S/C17H12ClNO2/c18-13-5-7-14(8-6-13)19-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,20H,(H,19,21)

SMILES Code: O=C(NC1=CC=C(Cl)C=C1)C2=C(O)C=C3C=CC=CC3=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Jiang M, Yan Y, Yang K, Liu Z, Qi J, Zhou H, Qian N, Zhou Q, Wang T, Xu X, Xiao X, Deng L. Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis. J Cell Mol Med. 2019 Feb;23(2):1224-1234. doi: 10.1111/jcmm.14024. Epub 2018 Nov 20. PubMed PMID: 30461194; PubMed Central PMCID: PMC6349349.