Sarcolysine hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573629

CAS#: 1465-26-5

Description: Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.


Chemical Structure

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Sarcolysine hydrochloride
CAS# 1465-26-5

Theoretical Analysis

MedKoo Cat#: 573629
Name: Sarcolysine hydrochloride
CAS#: 1465-26-5
Chemical Formula: C13H19Cl3N2O2
Exact Mass: 340.0512
Molecular Weight: 341.66
Elemental Analysis: C, 45.70; H, 5.61; Cl, 31.13; N, 8.20; O, 9.37

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: AI3-52155, Alkeran, DL-Phenylalanine mustard hydrochloride, DL-Sarcolysin monohydrochloride, DL-Sarcolysine hydrochloride, Melphalan, Sarcolysine hydrochloride, Sarcolysine HCl

IUPAC/Chemical Name: Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, hydrochloride, DL

InChi Key: OUUYBRCCFUEMLH-UHFFFAOYSA-N

InChi Code: 1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H

SMILES Code: Cl.NC(Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 341.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Esma F, Salvini M, Troia R, Boccadoro M, Larocca A, Pautasso C. Melphalan hydrochloride for the treatment of multiple myeloma. Expert Opin Pharmacother. 2017 Aug;18(11):1127-1136. doi: 10.1080/14656566.2017.1349102. Epub 2017 Jul 10. Review. PubMed PMID: 28658983.

2: Singh R, Chen J, Miller T, Bergren M, Mallik R. Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection. Pharm Dev Technol. 2018 Dec;23(10):1024-1029. doi: 10.1080/10837450.2016.1265557. Epub 2016 Dec 14. PubMed PMID: 27973975.