WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573623
CAS#: 2260-50-6
Description: Acetylcholine iodide is an endogenous neurotransmitter at cholinergic synapses. Acetylcholine iodide amplifies the action potential of the sarcolemma thereby inducing muscle contractions.
MedKoo Cat#: 573623
Name: Acetylcholine iodide
CAS#: 2260-50-6
Chemical Formula: C7H16INO2
Exact Mass: 273.0226
Molecular Weight: 273.11
Elemental Analysis: C, 30.78; H, 5.91; I, 46.47; N, 5.13; O, 11.72
Synonym: Acetylcholine iodide, AI3-51677; Choline, iodide, acetate (ester)
IUPAC/Chemical Name: (2-Acetoxyethyl)trimethylammonium iodide
InChi Key: SMBBQHHYSLHDHF-UHFFFAOYSA-M
InChi Code: 1S/C7H16NO2.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
SMILES Code: [N+](CCOC(C)=O)(C)(C)C.[IH-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 273.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Yoder RM, Chan JHM, Taube JS. Acetylcholine contributes to the integration of self-movement cues in head direction cells. Behav Neurosci. 2017 Aug;131(4):312-24. doi: 10.1037/bne0000205. PubMed PMID: 28714717; PubMed Central PMCID: PMC5535758.
2: Williamson PT, Verhoeven A, Miller KW, Meier BH, Watts A. The conformation of acetylcholine at its target site in the membrane-embedded nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18031-6. Epub 2007 Nov 7. PubMed PMID: 17989232; PubMed Central PMCID: PMC2084291.
3: Spence VA, Khan F, Kennedy G, Abbot NC, Belch JJ. Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004 Apr;70(4):403-7. Review. PubMed PMID: 15041034.
