WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573601
Description: Gallein is a Gβγ subunit signalling inhibitor which has been shown to inhibit metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand.
MedKoo Cat#: 573601
Chemical Formula: C20H12O7
Exact Mass: 364.0583
Molecular Weight: 364.31
Elemental Analysis: C, 65.94; H, 3.32; O, 30.74
Synonym: 4,5-Dihydroxyfluorescein, AI3-63042, Gallein, Pyrogallolphthalein
IUPAC/Chemical Name: 3',4',5',6'-Tetrahydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one
InChi Key: PHLYOKFVXIVOJC-UHFFFAOYSA-N
InChi Code: 1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H
SMILES Code: C12(c3c(c(O)c(cc3)O)Oc3c1ccc(O)c3O)OC(=O)c1c2cccc1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 364.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Sanz G, Leray I, Muscat A, Acquistapace A, Cui T, Rivière J, Vincent-Naulleau S, Giandomenico V, Mir LM. Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10(1):541. doi: 10.1186/s13104-017-2879-z. PubMed PMID: 29084601; PubMed Central PMCID: PMC5663063.