WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573591
Description: Orazamide is a therapeutic drug that may be useful in the treatment of chronic hepatitis and various skin diseases.
MedKoo Cat#: 573591
Chemical Formula: C9H14N6O7
Exact Mass: 318.0924
Molecular Weight: 318.25
Elemental Analysis: C, 33.97; H, 4.43; N, 26.41; O, 35.19
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Aica orotate dihydrate, Aicamin dihydrate, Aicorat dihydrate, Orazamide, Orazamide dihydrate
IUPAC/Chemical Name: 1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid, compoundwith 5-amino-1H-imidazole-4-carboxamide (1:1) dihydrate
InChi Key: PVCSUEOGEIOUHG-UHFFFAOYSA-N
InChi Code: 1S/C5H4N2O4.C4H6N4O/c8-3-1-2(4(9)10)6-5(11)7-3;5-3-2(4(6)9)7-1-8-3/h1H,(H,9,10)(H2,6,7,8,11);1H,5H2,(H2,6,9)(H,7,8)
SMILES Code: NC(=O)c1nc[nH]c1N.OC(=O)C2=CC(=O)NC(=O)N2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 318.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Chen X, Jing J, Ren W, Han DE, Jing N, Wang G. Determination of 5-aminoimidazole-4-carboxamide in human plasma by ion-pair extraction and LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Aug 15;855(2):140-4. Epub 2007 May 10. PubMed PMID: 17561451.
2: Pár A, Paál M, Kádas I, Nagy I, Kerekes E, Jávor T. Experiences with Catergen treatment in chronic active hepatitis. Ther Hung. 1983;31(3):105-14. PubMed PMID: 6400472.
3: Roda E, Sama C, Festi D. [Controlled clinical evaluation of the therapeutic effectiveness of AICA orotate in chronic hepatitis]. Clin Ter. 1979 Jun 15;89(5):489-93. Italian. PubMed PMID: 535326.
4: MIYAZAWA T, KUMASAKA S. [THE PHARMACOLOGICAL ACTIVITY OF AICA OROTATE IN VARIOUS SKIN DISEASES]. Hifuka Kiyo. 1965 Feb;60:76-84. Japanese. PubMed PMID: 14286713.