Orf 17910

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584939

CAS#: 87107-94-6

Description: Orf 17910 is a histamine H2-receptor antagonist.

Chemical Structure

Orf 17910
CAS# 87107-94-6

Theoretical Analysis

MedKoo Cat#: 584939
Name: Orf 17910
CAS#: 87107-94-6
Chemical Formula: C18H27N5O2S
Exact Mass: 377.19
Molecular Weight: 377.507
Elemental Analysis: C, 57.27; H, 7.21; N, 18.55; O, 8.48; S, 8.49

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Orf 17910; Orf17910; Orf-17910

IUPAC/Chemical Name: 1,2,5-Thiadiazole-3,4-diamine, N-(3-(3-((4-methyl-1-piperidinyl)methyl)phenoxy)propyl)-, 1-oxide


InChi Code: InChI=1S/C18H27N5O2S/c1-14-6-9-23(10-7-14)13-15-4-2-5-16(12-15)25-11-3-8-20-18-17(19)21-26(24)22-18/h2,4-5,12,14H,3,6-11,13H2,1H3,(H2,19,21)(H,20,22)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 377.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Katz LB, Scott CK, Shriver DA. Pharmacological comparison of ORF 17910, a potent, long-acting histamine H2-receptor antagonist, to cimetidine and ranitidine. J Pharmacol Exp Ther. 1986 Aug;238(2):587-93. PubMed PMID: 2874214.

2: Huang SM, Tran-Phan H. High-performance liquid chromatographic determination of a new H2 blocker (ORF 17 910) in plasma. J Chromatogr. 1987 Dec 25;423:358-64. PubMed PMID: 2895116.