WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584939
Description: Orf 17910 is a histamine H2-receptor antagonist.
MedKoo Cat#: 584939
Name: Orf 17910
Chemical Formula: C18H27N5O2S
Exact Mass: 377.1885
Molecular Weight: 377.507
Elemental Analysis: C, 57.27; H, 7.21; N, 18.55; O, 8.48; S, 8.49
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Orf 17910; Orf17910; Orf-17910
IUPAC/Chemical Name: 1,2,5-Thiadiazole-3,4-diamine, N-(3-(3-((4-methyl-1-piperidinyl)methyl)phenoxy)propyl)-, 1-oxide
InChi Key: PPMYJUCFCTXGKV-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H27N5O2S/c1-14-6-9-23(10-7-14)13-15-4-2-5-16(12-15)25-11-3-8-20-18-17(19)21-26(24)22-18/h2,4-5,12,14H,3,6-11,13H2,1H3,(H2,19,21)(H,20,22)
SMILES Code: NC1=NS(N=C1NCCCOC2=CC=CC(CN3CCC(C)CC3)=C2)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 377.507 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Katz LB, Scott CK, Shriver DA. Pharmacological comparison of ORF 17910, a potent, long-acting histamine H2-receptor antagonist, to cimetidine and ranitidine. J Pharmacol Exp Ther. 1986 Aug;238(2):587-93. PubMed PMID: 2874214.
2: Huang SM, Tran-Phan H. High-performance liquid chromatographic determination of a new H2 blocker (ORF 17 910) in plasma. J Chromatogr. 1987 Dec 25;423:358-64. PubMed PMID: 2895116.