Orf 17578

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584936

CAS#: 75438-42-5

Description: Orf 17578 is a histamine H2-receptor antagonist.

Chemical Structure

Orf 17578
CAS# 75438-42-5

Theoretical Analysis

MedKoo Cat#: 584936
Name: Orf 17578
CAS#: 75438-42-5
Chemical Formula: C15H22N4O3S
Exact Mass: 338.1413
Molecular Weight: 338.426
Elemental Analysis: C, 53.24; H, 6.55; N, 16.56; O, 14.18; S, 9.47

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Orf 17578; Orf-17578; Orf17578

IUPAC/Chemical Name: 1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-2-nitro-N'-2-propynyl-


InChi Code: InChI=1S/C15H22N4O3S/c1-4-7-16-15(11-19(20)21)17-8-9-23-12-14-6-5-13(22-14)10-18(2)3/h1,5-6,11,16-17H,7-10,12H2,2-3H3/b15-11+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 338.426 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Katz LB, Scott CK, Shriver DA. Pharmacology of ORF 17578, a new histamine H2-receptor antagonist: comparison with cimetidine and ranitidine. J Pharmacol Exp Ther. 1986 May;237(2):404-10. PubMed PMID: 2871172.

2: Kosh JW, Sowell JW, Chapman JM. A comparison of the cholinergic activity of selected H2-antagonists and sulfoxide metabolites. Pharm Res. 1989 Aug;6(8):709-13. PubMed PMID: 2573049.

3: Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar;29(3):285-90. PubMed PMID: 1970132.