WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573581
Description: alpha-Clopenthixol dihydrochloride is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
MedKoo Cat#: 573581
Name: alpha-Clopenthixol dihydrochloride
Chemical Formula: C22H27Cl3N2OS
Exact Mass: 472.091
Molecular Weight: 473.88
Elemental Analysis: C, 55.76; H, 5.74; Cl, 22.44; N, 5.91; O, 3.38; S, 6.77
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: alpha-Clopenthixol dihydrochloride, AY 62021, Chlorpenthixol dihydrochloride, Chlorperphenthixene dihydrochloride, Ciatyl, Clopenthixol dihydrochloride, Clopenthixol HCl, N 746, N-746, Sordenac, W 2304
IUPAC/Chemical Name: 1-Piperazineethanol, 4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride (9CI)
InChi Key: LPWNZMIBFHMYMX-MHKBYHAFSA-N
InChi Code: 1S/C22H25ClN2OS.2ClH/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26;;/h1-2,4-8,16,26H,3,9-15H2;2*1H/b18-5-
SMILES Code: c1ccc2c(c1)/C(=C/CCN3CCN(CC3)CCO)/c4cc(ccc4S2)Cl.Cl.Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 473.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Aaes-Jørgensen T, Gravem A, Jørgensen A. Serum levels of the isomers of clopenthixol in patients given cis(Z)-clopenthixol or cis(Z)/trans(E)-clopenthixol. Acta Psychiatr Scand Suppl. 1981;294:70-7. PubMed PMID: 6951396.
2: Aaes-Jørgensen T. Serum concentrations of cis(Z)- and trans(E)-clopenthixol after administration of cis(Z)-clopenthixol and clopenthixol to human volunteers. Acta Psychiatr Scand Suppl. 1981;294:64-9. PubMed PMID: 6951395.