WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584933

CAS#: 468-61-1

Description: Oxeladin is an antitussive agent.

Chemical Structure

CAS# 468-61-1

Theoretical Analysis

MedKoo Cat#: 584933
Name: Oxeladin
CAS#: 468-61-1
Chemical Formula: C20H33NO3
Exact Mass: 335.246
Molecular Weight: 335.488
Elemental Analysis: C, 71.60; H, 9.92; N, 4.18; O, 14.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Oxeladin; EC 207-412-1; Oxeladina; Oxeladine; Oxeladinum

IUPAC/Chemical Name: 2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate


InChi Code: InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 335.488 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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1: Lartigue-Mattei C, Galmier MJ, Chabard JL, Beyssac E, Aiache JM. Determination of oxeladin in human plasma by gas chromatography--mass spectrometry. Biomed Chromatogr. 1995 Jan-Feb;9(1):32-5. PubMed PMID: 7734931.

2: DAVID A, LEITH-ROSS F, VALLANCE DK. Antitussive and other pharmacological properties of the diethylaminoethoxyethyl ester of alpha alpha-diethylphenylacetic acid, (oxeladin). J Pharm Pharmacol. 1957 Jul;9(7):446-58. PubMed PMID: 13439531.

3: El-Gindy A. High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products. Farmaco. 2005 Aug;60(8):689-99. PubMed PMID: 16023117.

4: Takagi K, Yuizono T, Kasé Y. [On the site of antitussive action of 2-(2-diethylaminoethoxy)ethyl alpha,alpha-diethylphenylacetate (Oxeladin)]. Yakugaku Zasshi. 1967 Aug;87(8):898-906. Japanese. PubMed PMID: 5625837.

5: Salvesen B, Haugland T. Determination of oxeladin in human sera by gas--liquid chromatography with thermionic detection. J Chromatogr. 1981 Oct 9;225(2):463-8. PubMed PMID: 7298782.

6: OZAWA H, FUKUDA H, OTSUKI I, CHIBA S. [Antitussive activity and acute toxicity of 2-(2-diethylamino-ethoxy)ethyl alpha,alpha-diethylphenylacetate (oxeladin)]. Yakugaku Zasshi. 1962 Sep;82:1314-7. Japanese. PubMed PMID: 13940888.

7: Knopp C, Korsatko W. [Determination of oxeladin citrate in drug combinations]. Pharmazie. 1982 Jan;37(1):76-7. German. PubMed PMID: 7071116.

8: Tarayre JP, Vilain P, Lauressergues H, Cauquil J, Bru M, Caillol V, Pouget G, Jougla AM, Go M. Pharmacological study of the antitussive and respiratory-analeptic properties of N-(2'-ethylpyrrolidino)diphenylacetamide hydrochloride (F 1459). Arzneimittelforschung. 1983;33(7):931-5. PubMed PMID: 6684929.