Oxamarin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584931

CAS#: 15301-80-1 (free base)

Description: Oxamarin is used in treatment of varicose veins.


Chemical Structure

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Oxamarin
CAS# 15301-80-1 (free base)

Theoretical Analysis

MedKoo Cat#: 584931
Name: Oxamarin
CAS#: 15301-80-1 (free base)
Chemical Formula: C22H34N2O4
Exact Mass: 390.25
Molecular Weight: 390.524
Elemental Analysis: C, 67.66; H, 8.78; N, 7.17; O, 16.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 6830-17-7 (HCl); 15301-80-1 (free base)  

Synonym: Oxamarin; Oxamarine; Ossamarina; Oxamarin; Oxamarina

IUPAC/Chemical Name: 2H-1-Benzopyran-2-one, 6,7-bis(2-(diethylamino)ethoxy)-4-methyl-

InChi Key: KDZPIXVLPYVHDO-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H34N2O4/c1-6-23(7-2)10-12-26-20-15-18-17(5)14-22(25)28-19(18)16-21(20)27-13-11-24(8-3)9-4/h14-16H,6-13H2,1-5H3

SMILES Code: O=C1C=C(C)C2=CC(OCCN(CC)CC)=C(OCCN(CC)CC)C=C2O1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 390.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ciaceri G, Pennisi G. [Protective action of oxamarine in experimental arthropathy due to tubercullar bacilli]. Boll Chim Farm. 1972 Oct;111(10):626-30. Italian. PubMed PMID: 4630139.

2: Ciaceri G, Marini P. [Transcutaneous absorption of oxamarin (4-methyl-6,7-(bis-diethylaminoethoxy)-coumarin)]. Boll Chim Farm. 1972 May;111(5):321-7. Italian. PubMed PMID: 5050929.

3: Frandoli G, Turazza G, Spreafico PL. Comparative investigations on the treatment of the varicose syndrome with 4-methyl-6,7-(bis-beta-diethyl-aminoethoxy)-coumarine hydrochloride (oxamarine), with the disodium salt of disulphuric ester of 4-methyl-aesculetol and with tri-hydroxy-ethylrutoside (troxerutin). Panminerva Med. 1972 Sep;14(9):290-5. PubMed PMID: 4618898.