WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 573570
Description: A-923 is an H3 antagonist with effects on cognition.
MedKoo Cat#: 573570
Chemical Formula: C24H38N2O3
Exact Mass: 402.2882
Molecular Weight: 402.58
Elemental Analysis: C, 71.60; H, 9.51; N, 6.96; O, 11.92
This product is not in stock, which may be available by custom synthesis.
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Synonym: A-923, A 923, A923
IUPAC/Chemical Name: 1-(4-(3-(4-butyrylpiperazin-1-yl)propoxy)phenyl)heptan-1-one
InChi Key: JRVAWASJYLPUII-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H38N2O3/c1-3-5-6-7-10-23(27)21-11-13-22(14-12-21)29-20-8-15-25-16-18-26(19-17-25)24(28)9-4-2/h11-14H,3-10,15-20H2,1-2H3
SMILES Code: CCCC(N1CCN(CCCOC2=CC=C(C(CCCCCC)=O)C=C2)CC1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 402.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Berlin M, Boyce CW, Ruiz Mde L. Histamine H3 receptor as a drug discovery target. J Med Chem. 2011 Jan 13;54(1):26-53. doi: 10.1021/jm100064d. Epub 2010 Nov 9. Review. PubMed PMID: 21062081.