Olaflur HF

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MedKoo CAT#: 584928

CAS#: 6818-37-7 (HF)

Description: Olaflur (INN, or amine fluoride 297) is a fluoride-containing substance that is an ingredient of toothpastes and solutions for the prevention of dental caries. It has been in use since 1966. Especially in combination with dectaflur, it is also used in the form of gels for the treatment of early stages of caries, sensitive teeth, and by dentists for the refluoridation of damaged tooth enamel. Olaflur is a salt consisting of an alkyl ammonium cation and fluoride as the counterion. With a long lipophilic hydrocarbon chain, the cation has surfactant properties. It forms a film layer on the surface of teeth, which facilitates incorporation of fluoride into the enamel. The top layers of the enamel's primary mineral, hydroxylapatite, are converted into the more robust fluorapatite.

Chemical Structure

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Olaflur HF
CAS# 6818-37-7 (HF)
Instruction

Theoretical Analysis

MedKoo Cat#: 584928
Name: Olaflur HF
CAS#: 6818-37-7 (HF)
Chemical Formula: C27H60F2N2O3
Exact Mass: 0.00
Molecular Weight: 498.785
Elemental Analysis: C, 65.02; H, 12.13; F, 7.62; N, 5.62; O, 9.62

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 6818-37-7 (HF)   7671-49-7 (free base)    

Synonym: Olaflur; AmF 297; Amine fluoride; Amine fluoride 297; GA 297; OlaFluor; Olaflur; SKF 38095J2;

IUPAC/Chemical Name: Ethanol, 2,2'-[[3-[(2-hydroxyethyl)octadecylamino]propyl]imino]bis-, dihydrofluoride

InChi Key: ZVVSSOQAYNYNPP-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H58N2O3.2FH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-28(22-25-30)20-18-21-29(23-26-31)24-27-32;;/h30-32H,2-27H2,1H3;2*1H

SMILES Code: CCCCCCCCCCCCCCCCCCN(CCCN(CCO)CCO)CCO.[H]F.[H]F

Appearance: This product will be supplied as aqueous solution (concentration TBD)

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 498.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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