Ono 11006

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584913

CAS#: 73509-46-3

Description: Ono 11006 is a thromboxane agonist that dose dependently reduced the positive inotropic effect induced by field stimulation.

Chemical Structure

Ono 11006
CAS# 73509-46-3

Theoretical Analysis

MedKoo Cat#: 584913
Name: Ono 11006
CAS#: 73509-46-3
Chemical Formula: C22H36O3
Exact Mass: 348.2664
Molecular Weight: 348.527
Elemental Analysis: C, 75.82; H, 10.41; O, 13.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ono 11006; Ono-11006; Ono11006

IUPAC/Chemical Name: 5-Heptenoic acid, 7-(3-(3-hydroxy-1-octenyl)bicyclo(3.1.1)hept-2-yl)-, (2alpha(Z),3beta(1E,3S*))-(+-)-


InChi Code: InChI=1S/C22H36O3/c1-2-3-6-9-20(23)13-12-18-14-17-15-19(16-17)21(18)10-7-4-5-8-11-22(24)25/h4,7,12-13,17-21,23H,2-3,5-6,8-11,14-16H2,1H3,(H,24,25)/b7-4-,13-12+/t17?,18-,19?,20?,21-/m1/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 348.527 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Mantelli L, Amerini S, Rubino A, Ledda F. Effects of thromboxane agonists on cardiac adrenergic neurotransmission. Eur J Pharmacol. 1992 Mar 17;213(1):79-85. PubMed PMID: 1323473.

2: Nakahata N, Takano H, Ohizumi Y. Thromboxane A2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles. Life Sci. 2000;66(5):PL 71-6. PubMed PMID: 10670835.