WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584910
CAS#: 143460-23-5
Description: Oncopterin is found in urine from patients with solid and blood cancers.
MedKoo Cat#: 584910
Name: Oncopterin
CAS#: 143460-23-5
Chemical Formula: C12H18N6O3
Exact Mass: 294.144
Molecular Weight: 294.315
Elemental Analysis: C, 48.97; H, 6.16; N, 28.56; O, 16.31
This product is not in stock, which may be available by custom synthesis.
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Synonym: Oncopterin
IUPAC/Chemical Name: 4(1H)-Pteridinone, 2-((3-aminopropyl)amino)-6-(1,2-dihydroxypropyl)-, (R-(R*,S*))-
InChi Key: BBFMPNKVCFIPPX-RCOVLWMOSA-N
InChi Code: InChI=1S/C12H18N6O3/c1-6(19)9(20)7-5-15-10-8(16-7)11(21)18-12(17-10)14-4-2-3-13/h5-6,9,19-20H,2-4,13H2,1H3,(H2,14,15,17,18,21)/t6-,9-/m0/s1
SMILES Code: O=C1N=C(NCCCN)NC2=NC=C([C@@H](O)[C@@H](O)C)N=C12
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 294.315 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Hibiya M, Teradaira R, Shimpo K, Matsui T, Sugimoto T, Nagatsu T. Interference of a methotrexate derivative with urinary oncopterin [N2-(3-aminopropyl)biopterin] measurement by high-performance liquid chromatography with fluorimetric detection. J Chromatogr B Biomed Sci Appl. 1997 Mar 28;691(1):223-7. PubMed PMID: 9140780.
2: Hibiya M, Teradaira R, Sugimoto T, Fujita K, Nagatsu T. Simultaneous determination of N2-(3-aminopropyl)biopterin (oncopterin), biopterin and neopterin by high-performance liquid chromatography with fluorescence detection. J Chromatogr B Biomed Appl. 1995 Oct 6;672(1):143-8. PubMed PMID: 8590927.
3: Ogiwara S, Hidaka H, Sugimoto T, Teradaira R, Fujita K, Nagatsu T. Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers. J Biochem. 1993 Jan;113(1):1-3. PubMed PMID: 8384199.
4: Tomandl J. [Oncopterin in clinical diagnosis]. Vnitr Lek. 1997 Jun;43(6):404-6. Review. Czech. PubMed PMID: 9601874.
5: Shimpo K, Chihara T, Hibiya M, Ito S, Nagatsu T. [Amines and pteridines]. Nihon Rinsho. 1996 Jun;54(6):1515-20. Review. Japanese. PubMed PMID: 8691603.
