WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 565194
Description: AAL1 is an inhibitor of dark-grown Arabidopsis thaliana seedlings, functioning through auxin receptor Transport Inhibitor Response1 (TIR1) and depending on auxin influx and efflux carriers.
MedKoo Cat#: 565194
Chemical Formula: C15H18N2O3S
Exact Mass: 306.1038
Molecular Weight: 306.38
Elemental Analysis: C, 58.80; H, 5.92; N, 9.14; O, 15.67; S, 10.46
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Auxin Activity Like 1; AAL-1; AAL 1; AAL1
IUPAC/Chemical Name: N-(4-Ethylphenyl)-2-(2-methyl-3,5-dioxothiomorpholino)acetamide
InChi Key: RPOCQUTXCSLYFJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H18N2O3S/c1-3-11-4-6-12(7-5-11)16-13(18)8-17-14(19)9-21-10(2)15(17)20/h4-7,10H,3,8-9H2,1-2H3,(H,16,18)
SMILES Code: O=C(NC1=CC=C(CC)C=C1)CN2C(C(C)SCC2=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 306.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Li W, Li H, Xu P, Xie Z, Ye Y, Li L, Li D, Zhang Y, Li L, Zhao Y. Identification of Auxin Activity Like 1, a chemical with weak functions in auxin signaling pathway. Plant Mol Biol. 2018 Oct;98(3):275-287. doi: 10.1007/s11103-018-0779-9. Epub 2018 Oct 11. PubMed PMID: 30311174.
2: Taira Y, Okegawa Y, Sugimoto K, Abe M, Miyoshi H, Shikanai T. Antimycin A-like molecules inhibit cyclic electron transport around photosystem I in ruptured chloroplasts. FEBS Open Bio. 2013 Sep 30;3:406-10. doi: 10.1016/j.fob.2013.09.007. eCollection 2013. PubMed PMID: 24251103; PubMed Central PMCID: PMC3821020.
3: Raghavan KS, Gray DB, Scholz TH, Nemeth GA, Hussain MA. Degradation kinetics of DMP 777, an elastase inhibitor. Pharm Res. 1996 Dec;13(12):1815-20. PubMed PMID: 8987077.