NA 0359

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MedKoo CAT#: 584882

CAS#: 134931-91-2

Description: NA 0359 is an indolocarbazole and a derivative of SF 2370 that inhibits smooth muscle contraction.


Price and Availability

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Pricing updated 2020-09-20. Prices are subject to change without notice.

NA 0359 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584882
Name: NA 0359
CAS#: 134931-91-2
Chemical Formula: C29H30N4O3
Exact Mass: 482.2318
Molecular Weight: 482.584
Elemental Analysis: C, 72.18; H, 6.27; N, 11.61; O, 9.95


Synonym: NA 0359; NA0359; NA-0359

IUPAC/Chemical Name: 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-10-((propylamino)methyl)-, (9S-(9alpha,10beta,12alpha))-

InChi Key: RWWCVQJGKUASET-RAAODGORSA-N

InChi Code: InChI=1S/C29H30N4O3/c1-3-11-30-16-33(35)22-13-17-8-9-18(22)24-19-14-31-15-20(19)25-26-21(6-4-7-23(26)34)32(27(25)28(24)33)12-5-10-29(33,2)36-17/h5-6,8-10,14-15,17,30,35H,3-4,7,11-13,16H2,1-2H3/b10-5-/t17-,29+/m1/s1

SMILES Code: O=C(CCC=C12)C1=C3C4=CN=CC4=C5C6=C3N2C/C=C\[C@@](O7)(C)N6(CNCCC)(O)C8=C5C=C[C@]7([H])C8


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Kohama K, Hiramura T, Takano-Ohmuro H, Ozaki H, Karaki H, Hachisu M. Effects of NA0344, a new smooth muscle relaxant, on the actin-myosin-ATP interaction and myosin light chain phosphorylation in vitro. Gen Pharmacol. 1991;22(3):465-74. PubMed PMID: 1869018.