WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584882
CAS#: 134931-91-2
Description: NA 0359 is an indolocarbazole and a derivative of SF 2370 that inhibits smooth muscle contraction.
MedKoo Cat#: 584882
Name: NA 0359
CAS#: 134931-91-2
Chemical Formula: C29H30N4O3
Exact Mass: 482.2318
Molecular Weight: 482.584
Elemental Analysis: C, 72.18; H, 6.27; N, 11.61; O, 9.95
This product is not in stock, which may be available by custom synthesis.
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Synonym: NA 0359; NA0359; NA-0359
IUPAC/Chemical Name: 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-10-((propylamino)methyl)-, (9S-(9alpha,10beta,12alpha))-
InChi Key: RWWCVQJGKUASET-RAAODGORSA-N
InChi Code: InChI=1S/C29H30N4O3/c1-3-11-30-16-33(35)22-13-17-8-9-18(22)24-19-14-31-15-20(19)25-26-21(6-4-7-23(26)34)32(27(25)28(24)33)12-5-10-29(33,2)36-17/h5-6,8-10,14-15,17,30,35H,3-4,7,11-13,16H2,1-2H3/b10-5-/t17-,29+/m1/s1
SMILES Code: O=C(CCC=C12)C1=C3C4=CN=CC4=C5C6=C3N2C/C=C\[C@@](O7)(C)N6(CNCCC)(O)C8=C5C=C[C@]7([H])C8
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 482.584 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Kohama K, Hiramura T, Takano-Ohmuro H, Ozaki H, Karaki H, Hachisu M. Effects of NA0344, a new smooth muscle relaxant, on the actin-myosin-ATP interaction and myosin light chain phosphorylation in vitro. Gen Pharmacol. 1991;22(3):465-74. PubMed PMID: 1869018.
