Niruriside

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MedKoo CAT#: 584879

CAS#: 173268-90-1

Description: Niruriside inhibits binding of REV protein to RRE protein and is isolated from Phyllanthus niruri.


Price and Availability

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Pricing updated 2020-11-23. Prices are subject to change without notice.

Niruriside is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584879
Name: Niruriside
CAS#: 173268-90-1
Chemical Formula: C38H42O17
Exact Mass: 770.2422
Molecular Weight: 770.737
Elemental Analysis: C, 59.22; H, 5.49; O, 35.29


Synonym: Niruriside

IUPAC/Chemical Name: alpha-D-Glucopyranoside, 1-O-acetyl-3,6-bis-O-(1-oxo-3-phenyl-2-propenyl)-beta-D-fructofuranosyl, 2,4,6-triacetate, (E,E)-

InChi Key: KUZYDHCVYKUFKF-WBOICGRRSA-N

InChi Code: InChI=1S/C38H42O17/c1-22(39)47-20-29-34(50-24(3)41)33(46)35(51-25(4)42)37(52-29)55-38(21-49-23(2)40)36(53-31(44)18-16-27-13-9-6-10-14-27)32(45)28(54-38)19-48-30(43)17-15-26-11-7-5-8-12-26/h5-18,28-29,32-37,45-46H,19-21H2,1-4H3/b17-15+,18-16+/t28-,29-,32-,33+,34-,35-,36+,37-,38+/m1/s1

SMILES Code: O[C@@H]([C@H](OC(C)=O)[C@@H](COC(C)=O)O1)[C@@H](OC(C)=O)[C@H]1O[C@@]2(COC(C)=O)[C@H]([C@@H]([C@@H](COC(/C=C/C3=CC=CC=C3)=O)O2)O)OC(/C=C/C4=CC=CC=C4)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Qian-Cutrone J, Huang S, Trimble J, Li H, Lin PF, Alam M, Klohr SE, Kadow KF. Niruriside, a new HIV REV/RRE binding inhibitor from Phyllanthus niruri. J Nat Prod. 1996 Feb;59(2):196-9. PubMed PMID: 8991954.