Pyroxamine maleate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573495

CAS#: 5560-75-8 (maleate)

Description: Pyroxamine maleate is an antihistamine.

Chemical Structure

Pyroxamine maleate
CAS# 5560-75-8 (maleate)

Theoretical Analysis

MedKoo Cat#: 573495
Name: Pyroxamine maleate
CAS#: 5560-75-8 (maleate)
Chemical Formula: C22H24ClNO5
Exact Mass: 417.1343
Molecular Weight: 417.89
Elemental Analysis: C, 63.23; H, 5.79; Cl, 8.48; N, 3.35; O, 19.14

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 7009-68-9 (free base); 5560-75-8 (maleate)  

Synonym: Pyroxamine maleate

IUPAC/Chemical Name: Pyrrolidine, 3-((4-chlorophenyl)phenylmethoxy)-1-methyl-, (Z)-2-butenedioate (1:1)


InChi Code: 1S/C18H20ClNO.C4H4O4/c1-20-12-11-17(13-20)21-18(14-5-3-2-4-6-14)15-7-9-16(19)10-8-15;5-3(6)1-2-4(7)8/h2-10,17-18H,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code: CN1CCC(C1)OC(c2ccccc2)c3ccc(Cl)cc3.OC(=O)\C=C/C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 417.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Smits PH, De Haan M, Maat C, Grivell LA. The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene. Yeast. 1994 Apr;10 Suppl A:S75-80. PubMed PMID: 8091864.

2: THOMAS JW. Pyroxamine: a clinical study of a new antihistamine. Ann Allergy. 1961 Jul;19:760-5. PubMed PMID: 13776501.