Vesamicol hydrochloride, (+/-)-

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573492

CAS#: 120447-62-3

Description: Vesamicol hydrochloride, (+/-)- is an inhibitor of acetylcholine transport.

Chemical Structure

Vesamicol hydrochloride, (+/-)-
CAS# 120447-62-3

Theoretical Analysis

MedKoo Cat#: 573492
Name: Vesamicol hydrochloride, (+/-)-
CAS#: 120447-62-3
Chemical Formula: C17H26ClNO
Exact Mass: 295.1703
Molecular Weight: 295.85
Elemental Analysis: C, 69.02; H, 8.86; Cl, 11.98; N, 4.73; O, 5.41

Price and Availability

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250.0mg USD 300.0 2 Weeks
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Synonym: AH-5183 hydrochloride, Vesamicol hydrochloride, (+/-)-

IUPAC/Chemical Name: Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, hydrochloride, trans-(+/-)-


InChi Code: 1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H/t16-,17-;/m1./s1

SMILES Code: Cl.O[C@@H]1CCCC[C@H]1N2CCC(CC2)c3ccccc3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 295.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Marien MR, Richard JW, Allaire C, Altar CA. Suppression of in vivo neostriatal acetylcholine release by vesamicol: evidence for a functional role of vesamicol receptors in brain. J Neurochem. 1991 Dec;57(6):1878-83. PubMed PMID: 1658227.

2: Estrella D, Green KL, Prior C, Dempster J, Halliwell RF, Jacobs RS, Parsons SM, Parsons RL, Marshall IG. A further study of the neuromuscular effects of vesamicol (AH5183) and of its enantiomer specificity. Br J Pharmacol. 1988 Apr;93(4):759-68. PubMed PMID: 3260527; PubMed Central PMCID: PMC1853909.