Agigenin
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573469

CAS#: 55332-76-8

Description: Agigenin is a biochemical with antiproliferatice activity against human IGR-1 cells, important in malignant melanomas. Agigenin is also used in the synthesis of antifungal saponins.


Chemical Structure

img
Agigenin
CAS# 55332-76-8

Theoretical Analysis

MedKoo Cat#: 573469
Name: Agigenin
CAS#: 55332-76-8
Chemical Formula: C27H44O5
Exact Mass: 448.32
Molecular Weight: 448.640
Elemental Analysis: C, 72.28; H, 9.89; O, 17.83

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Agigenin

IUPAC/Chemical Name: Spirostan-2,3,6-triol, (2alpha,3beta,5alpha,6beta,25R)-

InChi Key: FYRLHXNMINIDCB-LEGLVIAUSA-N

InChi Code: 1S/C27H44O5/c1-14-5-8-27(31-13-14)15(2)24-23(32-27)11-18-16-9-20(28)19-10-21(29)22(30)12-26(19,4)17(16)6-7-25(18,24)3/h14-24,28-30H,5-13H2,1-4H3/t14-,15+,16-,17+,18+,19-,20-,21-,22-,23+,24+,25+,26-,27-/m1/s1

SMILES Code: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4C[C@H]([C@@H]6[C@@]5(C[C@H]([C@@H](C6)O)O)C)O)C)C)OC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 448.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Lanzotti V, Barile E, Antignani V, Bonanomi G, Scala F. Antifungal saponins from bulbs of garlic, Allium sativum L. var. Voghiera. Phytochemistry. 2012 Jun;78:126-34. doi: 10.1016/j.phytochem.2012.03.009. Epub 2012 Apr 16. PubMed PMID: 22513009.

2: Tian Y, Sun LM, Liu XQ, Li B, Wang Q, Dong JX. Anti-HBV active flavone glucosides from Euphorbia humifusa Willd. Fitoterapia. 2010 Oct;81(7):799-802. doi: 10.1016/j.fitote.2010.04.012. Epub 2010 May 5. PubMed PMID: 20450964.

3: Carotenuto A, Fattorusso E, Lanzotti V, Magno S, De Feo V, Carnuccio R, D'Acquisto F. Porrigenins A and B, novel cytotoxic and antiproliferative sapogenins isolated from Allium porrum. J Nat Prod. 1997 Oct;60(10):1003-7. PubMed PMID: 9358643.

4: Syrov VN, Kurmukov AG. [Experimental study of the anabolic activity of 6-ketoderivatives of certain natural sapogenins]. Farmakol Toksikol. 1976 Sep-Oct;39(5):631-5. Russian. PubMed PMID: 1028596.