NASTRp
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565050

CAS#: 2616-72-0

Description: NASTRp is an inhibitor of CREB-CBP complex which possesses anti-cancer effects along with cell cycle regulation, autophagy suppression, and endoplasmic reticulum stress.


Price and Availability

Size
Price

200mg
USD 265
Size
Price

Size
Price

NASTRp , purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data, and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 565050
Name: NASTRp
CAS#: 2616-72-0
Chemical Formula: C18H15ClNO5P
Exact Mass: 391.0376
Molecular Weight: 391.74
Elemental Analysis: C, 55.19; H, 3.86; Cl, 9.05; N, 3.58; O, 20.42; P, 7.91


Synonym: Naphthol AS-TR phosphate; NASTRp

IUPAC/Chemical Name: N-(4-Chloro-2-methylphenyl)-3-(phosphonooxy)-2-naphthalenecarboxamide

InChi Key: SHTFMUPUBYXPCD-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H15ClNO5P/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24/h2-10H,1H3,(H,20,21)(H2,22,23,24)

SMILES Code: O=C(C1=C(OP(O)(O)=O)C=C2C=CC=CC2=C1)NC3=CC=C(Cl)C=C3C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Lee JW, Park HS, Park SA, Ryu SH, Meng W, Jürgensmeier JM, Kurie JM, Hong WK, Boyer JL, Herbst RS, Koo JS. A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress. PLoS One. 2015 Apr 21;10(4):e0122628. doi: 10.1371/journal.pone.0122628. eCollection 2015. PubMed PMID: 25897662; PubMed Central PMCID: PMC4405579.