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MedKoo CAT#: 584842

CAS#: 84233-61-4

Description: Nesosteine is a mucoregulatory agent.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-22. Prices are subject to change without notice.

Nesosteine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 584842
Name: Nesosteine
CAS#: 84233-61-4
Chemical Formula: C11H11NO3S
Exact Mass: 237.046
Molecular Weight: 237.273
Elemental Analysis: C, 55.68; H, 4.67; N, 5.90; O, 20.23; S, 13.51

Synonym: Nesosteine

IUPAC/Chemical Name: o-(3-Thiazolidinylcarbonyl)benzoic acid


InChi Code: InChI=1S/C11H11NO3S/c13-10(12-5-6-16-7-12)8-3-1-2-4-9(8)11(14)15/h1-4H,5-7H2,(H,14,15)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Franchi-Micheli S, Luzzi S, Ciuffi M, Gori A, Castiglioni C, Zilletti L. Effects of nesosteine on Herxheimer microshock in guinea-pigs. Agents Actions. 1987 Apr;20(3-4):327-9. PubMed PMID: 2440286.

2: Braga PC, Bossi R, Castiglioni CL, Romandini S, Allegra L. Preliminary data on the action of nesosteine, a mucomodifying drug, on mucociliary transport. J Int Med Res. 1987 Jan-Feb;15(1):57-61. PubMed PMID: 3817282.

3: Scuri R, Mondani P, Frova C, Fantini L. Nesosteine: a new mucoregulatory agent. Drugs Exp Clin Res. 1986;12(8):663-70. PubMed PMID: 3757762.

4: Braga PC, Beghi G, Castelli C, Grasselli G, Ornaghi A, Rampoldi C, Zheng Y, Allegra L. Rheological profile of nesosteine: a new mucoactive agent. Int J Clin Pharmacol Res. 1989;9(1):77-83. PubMed PMID: 2707929.

5: Gatto PG, Gramolini C, Valenti S. [Effectiveness and tolerance of a new molecule with secreto-dynamic activity: nesosteine]. Clin Ter. 1989 Jan 31;128(2):87-97. Italian. PubMed PMID: 2523778.

6: Luini W, Sozzani S, D'Alessandro F, Zhang HX, Spreafico F. Stimulation of natural host defence mechanisms in rodents by nesosteine. Int J Immunopharmacol. 1988;10(1):59-65. PubMed PMID: 3366510.

7: Girometta MA, Loschi L, Ventura P. High-performance liquid chromatographic assay of nesosteine in human plasma and urine. J Chromatogr. 1989 Jan 27;487(1):117-24. PubMed PMID: 2715254.

8: Mbuyamba P. Clinical trial with CO-1177: a preliminary report. Int J Clin Pharmacol Res. 1986;6(2):119-21. PubMed PMID: 3522442.