N 1518

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584797

CAS#: 93750-14-2

Description: N 1518 has alpha, beta-adrenergic blocking, antihypertensive and vasodilating properties.


Price and Availability

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N 1518 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584797
Name: N 1518
CAS#: 93750-14-2
Chemical Formula: C22H26N2O5
Exact Mass: 398.1842
Molecular Weight: 398.459
Elemental Analysis: C, 66.32; H, 6.58; N, 7.03; O, 20.08


Synonym: N 1518; N1518; N-1518

IUPAC/Chemical Name: 1(2H)-Isoquinolinone, 4-(2-hydroxy-3-((2-(2-methoxyphenoxy)-1-methylethyl)amino)propoxy)-

InChi Key: BZAQSBHYQKDSGT-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H26N2O5/c1-15(13-28-20-10-6-5-9-19(20)27-2)23-11-16(25)14-29-21-12-24-22(26)18-8-4-3-7-17(18)21/h3-10,12,15-16,23,25H,11,13-14H2,1-2H3,(H,24,26)

SMILES Code: O=C1NC=C(OCC(O)CNC(C)COC2=CC=CC=C2OC)C3=C1C=CC=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934990300


References

1: Sugai T. [Pharmacological properties of (+/-)-4-[2-hydroxy-3-(3-(2-methoxyphenoxy)-2-propylamino)propoxy]-1(2H) -isoquinolinone (N-1518), a new combined alpha- and beta-adrenoceptor blocking drug]. Nihon Yakurigaku Zasshi. 1990 Sep;96(3):117-27. Japanese. PubMed PMID: 1980255.