NIR-HS

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564827

CAS#: NONE

Description: NIR-HS is a highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulfide in living cells and in mice.


Chemical Structure

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NIR-HS
CAS# NONE

Theoretical Analysis

MedKoo Cat#: 564827
Name: NIR-HS
CAS#: NONE
Chemical Formula: C34H32IN3O6
Exact Mass: 0.00
Molecular Weight: 705.550
Elemental Analysis: C, 57.88; H, 4.57; I, 17.99; N, 5.96; O, 13.61

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 2648306-76-5 (cation)    

Synonym: NIRHS; NIR HS; NIR-HS

IUPAC/Chemical Name: (E)-2-(2-(6-(2,4-Dinitrophenoxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide

InChi Key: OBQFEKRRPLICOT-IWSIBTJSSA-M

InChi Code: InChI=1S/C34H32N3O6.HI/c1-4-18-35-28-11-6-5-10-27(28)34(2,3)32(35)17-13-22-8-7-9-24-19-23-12-15-26(21-31(23)43-33(22)24)42-30-16-14-25(36(38)39)20-29(30)37(40)41;/h5-6,10-17,19-21H,4,7-9,18H2,1-3H3;1H/q+1;/p-1/b17-13+;

SMILES Code: CCC[N+]1=C(/C=C/C2=C3C(CCC2)=CC4=C(C=C(OC5=CC=C([N+]([O-])=O)C=C5[N+]([O-])=O)C=C4)O3)C(C)(C)C6=C1C=CC=C6.[I-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 705.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhou L, Lu D, Wang Q, Liu S, Lin Q, Sun H. Molecular engineering of a mitochondrial-targeting two-photon in and near-infrared out fluorescent probe for gaseous signal molecules H(2)S in deep tissue bioimaging. Biosens Bioelectron. 2017 May 15;91:699-705. doi: 10.1016/j.bios.2016.12.055. Epub 2016 Dec 28. PubMed PMID: 28126659.

2: Zhang L, Zheng XE, Zou F, Shang Y, Meng W, Lai E, Xu Z, Liu Y, Zhao J. A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice. Sci Rep. 2016 Jan 8;6:18868. doi: 10.1038/srep18868. PubMed PMID: 26743682; PubMed Central PMCID: PMC4705538.