NIR-HS

Orders received during 11/25~11/29 will be shipped in 11/30/2020 due to Thanksgiving holiday.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564827

CAS#: NONE

Description: NIR-HS is a highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulfide in living cells and in mice.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-11-25. Prices are subject to change without notice.

NIR-HS is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 564827
Name: NIR-HS
CAS#: NONE
Chemical Formula: C34H32IN3O6
Exact Mass:
Molecular Weight: 705.55
Elemental Analysis: C, 57.88; H, 4.57; I, 17.99; N, 5.96; O, 13.61


Synonym: NIRHS; NIR HS; NIR-HS

IUPAC/Chemical Name: (E)-2-(2-(6-(2,4-Dinitrophenoxy)-2,3-dihydro-1H-xanthen-4-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide

InChi Key: OBQFEKRRPLICOT-IWSIBTJSSA-M

InChi Code: InChI=1S/C34H32N3O6.HI/c1-4-18-35-28-11-6-5-10-27(28)34(2,3)32(35)17-13-22-8-7-9-24-19-23-12-15-26(21-31(23)43-33(22)24)42-30-16-14-25(36(38)39)20-29(30)37(40)41;/h5-6,10-17,19-21H,4,7-9,18H2,1-3H3;1H/q+1;/p-1/b17-13+;

SMILES Code: CCC[N+]1=C(/C=C/C2=C3C(CCC2)=CC4=C(C=C(OC5=CC=C([N+]([O-])=O)C=C5[N+]([O-])=O)C=C4)O3)C(C)(C)C6=C1C=CC=C6.[I-]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Zhou L, Lu D, Wang Q, Liu S, Lin Q, Sun H. Molecular engineering of a mitochondrial-targeting two-photon in and near-infrared out fluorescent probe for gaseous signal molecules H(2)S in deep tissue bioimaging. Biosens Bioelectron. 2017 May 15;91:699-705. doi: 10.1016/j.bios.2016.12.055. Epub 2016 Dec 28. PubMed PMID: 28126659.

2: Zhang L, Zheng XE, Zou F, Shang Y, Meng W, Lai E, Xu Z, Liu Y, Zhao J. A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice. Sci Rep. 2016 Jan 8;6:18868. doi: 10.1038/srep18868. PubMed PMID: 26743682; PubMed Central PMCID: PMC4705538.