Carboprost Tromethamine
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564800

CAS#: 58551-69-2

Description: Carboprost tromethamine is a Prostaglandin F2α analog.


Chemical Structure

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Carboprost Tromethamine
CAS# 58551-69-2

Theoretical Analysis

MedKoo Cat#: 564800
Name: Carboprost Tromethamine
CAS#: 58551-69-2
Chemical Formula: C25H47NO8
Exact Mass:
Molecular Weight: 489.65
Elemental Analysis: C, 61.32; H, 9.68; N, 2.86; O, 26.14

Price and Availability

Size Price Availability Quantity
10.0mg USD 405.0 2 Weeks
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Synonym: Carboprost tromethamine

IUPAC/Chemical Name: (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoate tris(hydroxymethyl)aminomethane salt

InChi Key: UMMADZJLZAPZAW-XOWPVRJPSA-N

InChi Code: InChI=1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5-,14-12+;/t16-,17-,18+,19-,21+;/m1./s1

SMILES Code: [NH3+]C(CO)(CO)CO.O=C([O-])CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@](C)(O)CCCCC)[C@H](O)C[C@@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 489.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ling Z, Yao L, Cui Z, Lifan C. Effect of carboprost tromethamine in prevention of postpartum hemorrhage in cesarean section. Pak J Pharm Sci. 2018 Sep;31(5(Special)):2257-2262. PubMed PMID: 30463821.

2: Meng W, Li R, Zha N, E L. Efficacy and safety of motherwort injection add-on therapy to carboprost tromethamine for prevention of post-partum blood loss: A meta-analysis of randomized controlled trials. J Obstet Gynaecol Res. 2019 Jan;45(1):47-56. doi: 10.1111/jog.13833. Epub 2018 Oct 4. Review. PubMed PMID: 30288846.

3: Habek JA, Habek D, Gulin D. REFRACTORY BRADYCARDIA--A RARE COMPLICATION OF CARBOPROST TROMETHAMINE FOR INDUCTION OF ABORTION. Acta Clin Croat. 2016 Jun;55(2):323-5. PubMed PMID: 28394550.

4: Zhang R, Shi H, Ren F, Yuan Z. Assessment of carboprost tromethamine for reducing hemorrhage in laparoscopic intramural myomectomy. Exp Ther Med. 2015 Sep;10(3):1171-1174. Epub 2015 Jul 20. PubMed PMID: 26622459; PubMed Central PMCID: PMC4533125.

5: Bai J, Sun Q, Zhai H. A comparison of oxytocin and carboprost tromethamine in the prevention of postpartum hemorrhage in high-risk patients undergoing cesarean delivery. Exp Ther Med. 2014 Jan;7(1):46-50. Epub 2013 Nov 1. PubMed PMID: 24348762; PubMed Central PMCID: PMC3861477.