WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564778


Description: ACAF4 is a neurotrophic agent which significantly increases survival in PC12 neuronal cells and enhances the effect of nerve growth factor (NGF). ACAF4 induces neurite outgrowth, and modulates ERK1/2 and AKT signaling pathways.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 564778
Name: ACAF4
Chemical Formula: C13H17NO3
Exact Mass: 235.1208
Molecular Weight: 235.28
Elemental Analysis: C, 66.36; H, 7.28; N, 5.95; O, 20.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ACAF-4; ACAF 4; ACAF4

IUPAC/Chemical Name: N-Butyl-3-(3,4-dihydroxy-phenyl)-acrylamide


InChi Code: InChI=1S/C13H17NO3/c1-2-3-8-14-13(17)7-5-10-4-6-11(15)12(16)9-10/h4-7,9,15-16H,2-3,8H2,1H3,(H,14,17)/b7-5+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 235.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Dilution Calculator

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1: Moosavi F, Hosseini R, Rajaian H, Silva T, Magalhães E Silva D, Saso L, Edraki N, Miri R, Borges F, Firuzi O. Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents. Bioorg Med Chem. 2017 Jun 15;25(12):3235-3246. doi: 10.1016/j.bmc.2017.04.026. Epub 2017 Apr 27. PubMed PMID: 28495385.