MB 05032
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584753

CAS#: 261365-11-1

Description: MB 05032 is a potent FBPase inhibitor that promotes HSC expansion.


Chemical Structure

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MB 05032
CAS# 261365-11-1

Theoretical Analysis

MedKoo Cat#: 584753
Name: MB 05032
CAS#: 261365-11-1
Chemical Formula: C11H15N2O4PS
Exact Mass: 302.049
Molecular Weight: 302.2848
Elemental Analysis: C, 43.71; H, 5.00; N, 9.27; O, 21.17; P, 10.25; S, 10.61

Price and Availability

Size Price Availability Quantity
10.0mg USD 390.0 2 Weeks
50.0mg USD 1160.0 2 Weeks
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Synonym: MB 05032; MB05032; MB-05032

IUPAC/Chemical Name: P-[5-[2-Amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphonic acid

InChi Key: XJMYIJPPDSZOPN-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14,15)16/h3-4,6H,5H2,1-2H3,(H2,12,13)(H2,14,15,16)

SMILES Code: OP(O)(C1=CC=C(C2=C(CC(C)C)SC(N)=N2)O1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 302.2848 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Guo et al (2018) Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis. Nat.Med. 24 360 PMID: 29377004

van Poelje et al (2011) Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes. Handb.Exp.Pharmacol. 203 279 PMID: 21484576

MB 05032

10.0mg / USD 390.0